Last updated on November 15, 2020
Olanzapine and fluoxetine curb resistance.
The combined administration of olanzapine (Zyprexa) and fluoxetine (Prozac) significantly reduced the symptoms of treatment-resistant depression and depression with psychotic features, compared to either agent as monotherapy. Treatment-resistant depression, defined as the failure of two or more adequate trials of two different classes of antidepressant treatments, is a significant public health concern.
Jennifer is a clinical pharmacologist. She helps doctors of all medical specialties choose medications. Jennifer consults about drug dosage, interactions, and side effects.