Last updated on May 12, 2023
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Duloxetine reduces symptoms of depression.
Duloxetine, an investi-gational antidepressant agent, called a dual reuptake inhibitor, was shown to be superior to placebo in reducing the severity of depressive symptoms. The Phase II data came from a multisite trial of 173 patients with major depression who randomly received either duloxetine, fluoxetine or placebo for eight weeks. The drug was well-tolerated.
Jennifer is a clinical pharmacologist. She helps doctors of all medical specialties choose medications. Jennifer consults about drug dosage, interactions, and side effects.