Drugs – Medical Products


Practically insoluble in water soluble in dichloromethane freely soluble in dimethylformamide sparingly soluble in methyl alcohol. Slightly soluble in water and in methyl alcohol very slightly soluble in alcohol freely soluble in dimethylformamide.

OTC Famotidine (Pepcid) for Acid Control

Johnson & Johnson-Merck has won the race to bring an H(2)-receptor antagonist to the over-the-counter (OTC) market. The joint pharmaceutical venture has received marketing approval for its 10-mg preparation of famotidine (Pepcid AC Acid Controller) from the Food and Drug Administration (FDA).


Rabeprazole sodium is a proton-pump inhibitor that suppresses gastric acid secretion by blocking acid (proton) pump within gastric parietal cells. It is indicated in short-term treatment in healing and symptomatic relief of duodenal ulcers and erosive or ulcerative gastroesophageal reflux disease (GERD); maintaining healing and reducing relapse rates of heartburn symptoms in patients with GERD; and treatment of daytime and nighttime heartburn and other symptoms associated with GERD; long-term treatment of pathological hypersecretory conditions, including Zollinger-Ellison syndrome and in combination with amoxicillin and clarithromycin to eradicate Helicobacter pylori. The most potent suppressors of gastric acid secretion are inhibitors of the gastric H+K+-ATPase (proton pump).

Palonosetron Hydrochloride

The stability of palonosetron hydrochloride at concentrations of 5 and 30 micrograms/mL was assessed in polyvinyl chloride bags of the following 4 infusion solutions: glucose 5%, sodium chloride 0.9%, glucose 5% in sodium chloride 0.45%, and glucose 5% in lactated Ringer’s solution. All solutions were considered to be physically and chemically stable for at least 48 hours at room temperature exposed to light, and for 14 days under refrigeration. As for Ondansetron, although no dosage reduction is considered necessary in hepatic impairment.

Imodium Instant Melts (Loperamide)

Imodium Instant Melts is a medicine which is used to treat sudden short-lived (acute) attacks of diarrhoea in adults and children aged 12 years and over. It can also be used to treat diarrhoea associated with Irritable Bowel Syndrome (IBS) in adults aged 18 years and over after your doctor has diagnosed you are suffering from this condition.

Roxatidine Acetate Hydrochloride

The stability of roxatidine acetate hydrochloride in parenteral nutrition solutions was influenced by storage temperature and amino acid content and composition. Unlike cimetidine roxatidine does not appear to affect cytochrome P450, and therefore is considered to have little effect on the metabolism of other drugs. However, like other H2-antagonists its effects on gastric pH may alter the absorption of some other drugs.

Antisecretory drugs

Antisecretory drugs are used in the treatment and prophylaxis of peptic ulcer disease (below) some are also employed in other disorders associated with gastric hyperacidity such as gastro-oesophageal reflux disease and dyspepsia (below). Histamine H2-receptor antagonists (H2-antagonists), which act by blocking histamine H2-receptors on gastric parietal cells, thereby antagonising the normal stimulatory effect of endogenous histamine on gastric acid production. Those described in mis site include cimeti-dine, famotidine, nizatidine, and ranitidine.

Boots Pharmacy Heartburn (Omeprazole)

This medicine can be taken by adults aged 18 years and over. However, some people should not take this medicine or should seek the advice of their pharmacist or doctor first. Driving and using machines: On rare occasions this medicine may cause drowsiness.


A white to slightly coloured powder. Slightly soluble in water soluble in methyl alcohol practically insoluble in heptane.

Carbenoxolone Sodium

BP 2008 (Carbenoxolone Sodium). A white or pale cream-coloured, hygroscopic powder. Freely soluble in water sparingly soluble in alcohol practically insoluble in chloroform and in ether.


Sparingly soluble in water very soluble in acid solutions. Sparingly soluble in water and in alcohol slightly soluble in dichloromethane soluble in methyl alcohol.

Janumet (Sitagliptin/Metformin Hydrochloride)

The name of your tablet is Janumet. It contains two different medicines called sitagliptin and metformin. They work together to control blood sugar levels in patients with a form of diabetes called ‘type 2 diabetes mellitus’.

Duphalac (Lactulose solution)

Duphalac contains a medicine called lactulose. This belongs to a group of medicines called laxatives. Duphalac is used to treat constipation.

Bismuth Compounds

Bismuth compounds have been used for their astringent and antidiarrhoeal properties in a variety of gastrointestinal disorders, and have been applied topically in skin disorders and anorectal disorders such as haemorrhoids. Certain salts are active against Helicobacter pylori and are used in the treatment of peptic ulcer disease.

Pirenzepine Hydrochloride

A white oryellowish crystalline powder. Freely soluble in water very slightly soluble in dehydrated alcohol practically insoluble in dichloromethane slightly soluble in methyl alcohol.


Sulfasalazine is a compound of a sulfonamide, sulfapyridine, with 5-aminosalicylic acid (mesalazine). Its activity is generally considered to lie in the 5-aminosalicylic acid moiety, which is released in the colon by bacterial metabolism, although intact sulfasalazine has some anti-inflammatory properties in its own right.

Mepradec (Omeprazole)

Treatment for heartburn (reflux oesophagitis and oesophageal reflux disease). For adults, the usual dose is omeprazole 20 mg once a day for 4 weeks.


Practically insoluble in water soluble in anhydrous alcohol very slightly soluble in acetonitrile. A white to brownish-white powder. Practically insoluble in water freely soluble in dimethylforma-mide.

Alizapride Hydrochloride

Alizapride is well absorbed from the gastrointestinal tract. It is mainly excreted unchanged in the urine and has an elimination half-life of about 3 hours.

Lotronex (Alosetron Hydrochloride)

Irritable bowel syndrome (IBS) is a disorder of the lower gastrointestinal tract characterized by symptoms such as diarrhea, diarrhea alternating with constipation, abdominal cramping and pain, gas and bloating, and mucus in the stool. IBS is one of the most common medical disorders in the U.