Pharmacopoeias. In Japan.
Aceglutamide aluminium, a complex of aceglutamide with aluminium hydroxide, is an antacid with general properties similar to those of aluminium hydroxide. It is given orally in a usual dose of 700 mg three times daily.
Муравьинокислый Алюминий; Формиат Алюминия
Al(CHO2)3,3H2O = 216.1.
CAS — 7360-53-4 (anhydrous aluminium formate).
Aluminium formate has astringent properties and has been used in topical preparations for mouth disorders.
Germany: Dynexan Zahnfleischtropfen.
Austria: Cional Dynexan Methyment
South Africa: Dynexan.
Pharmacopoeias. In British and US.
BP 2008 (Aluminium Glycinate). A white or almost white, odourless or almost odourless, powder. It contains 34.5 to 38.5% of Al203 calculated on the dried substance, and not more than 12% loss of weight on drying. Practically insoluble in water and in organic solvents it dissolves in dilute mineral acids and in aqueous solutions of alkali hydroxides. A 4% suspension in water has a pH of 6.5 to 7.5.
The United States Pharmacopeia 31, 2008 (Dihydroxyaluminum Aminoacetate). A white, odourless, powder. It may contain small amounts of aluminium oxide and aminoacetic acid. It loses not more than 14.5% of its weight on drying. Insoluble in water and in organic solvents soluble in dilute mineral acids and in solutions of fixed alkalis. A 4% suspension in water has apH of 6.5 to 7.5.
Aluminium glycinate is an antacid with general properties similar to those of aluminium hydroxide (below). It has been given in doses of up to 1 g by mouth.
The United States Pharmacopeia 31, 2008: Dihydroxyaluminum Aminoacetate Magma.
Spain: Gastroglutal Meteo-ril Natrocitral Secrepat.
Used as an adjunct in
Austria: Ambene N Indobene
Brazil: Reumix Somalgin
Chile: Butartrol Flexono
Germany: Indomet-ratiopharm m
Italy: Aspirina 03
Aluminium Hydroxide-Magnesium Carbonate Co-dried Gel
Aluminium hydroxide-magnesium carbonate co-dried gel is a co-precipitate of aluminium hydroxide and magnesium carbonate dried to contain a proportion of water for antacid activity. It is an antacid with general properties similar to those of aluminium hydroxide (above) and magnesium carbonate. It has been given in oral doses of about 450 to 900 mg, usually 3 times daily after meals and before bedtime.
Finland: Link PeeHoo
Greece: Regla pH
Indonesia: Stomacain Veragel
The Netherlands: Regla pH Remegel
Belgium: Barexal Nozid Regla pH Forte Syngel
Canada: Diovol Diovol Plus Gastrocalm Thunas Hyperacidity Tablets
Chile: Algicote Disfrutab Ditopax
Germany: Colina Spezial Duoventrinetten N
Hong Kong: Diovol Plus Simeco Veragel
Indonesia: Aludonna Di-Gel Farmacrol Gastran Oskamag Polycrol Simeco
Mexico: Algicon Ditopax Ditopax
The Netherlands: Algicon Muthesa N Rigoletten
Portugal: Di-Gel Di-Gel Forte
Singapore: Meclosil Veragel DMS
Spain: Acilene Acylene
Switzerland: Anacidol Andursil Gastropulgitef Refluxine
Thailand: Defomil Diovol Kremil Kremil-S Machto Simeco Veragel
UK: Algicon Simeco
Used as an adjunct in
Pharmacopoeias. In Vietnam. Europe includes hydrated aluminium phosphate and also a gel. US includes as a gel.
European Pharmacopoeia, 6th ed. (Aluminium Phosphate, Hydrated Aluminii Phosphas Hydricus Dried Aluminium Phosphate BP 2008). A white or almost white powder. Very slightly soluble in water practically insoluble in alcohol. It dissolves in dilute solutions of alkali hydroxides and mineral acids. A 4% suspension in water has a pH of 5.5 to 7.2. Store in airtight containers.
European Pharmacopoeia, 6th ed. (Aluminium Phosphate Gel Aluminii Phosphatis Li-quamen). It is aluminium phosphate in gel form containing 19 to 21% of A1P04. Practically insoluble in water, in alcohol, and in dichloromethane. It dissolves in dilute solutions of mineral acids. pH 6.0 to 8.0. Store in airtight containers.
The United States Pharmacopeia 31, 2008 (Aluminum Phosphate Gel). A 4 to 5% suspension of aluminium phosphate (AlPO4) in water and has a pH of 6.0 to 7.2. It is a white viscous suspension from which small amounts of water separate on standing. Store in airtight containers.
Aluminium phosphate is an antacid with general properties similar to those of aluminium hydroxide, but it does not produce phosphate depletion.
Aluminium phosphate is also used as an adjuvant in adsorbed vaccines.
The United States Pharmacopeia 31, 2008: Aluminum Phosphate Gel.
Czech Republic: Gasterin
France: Moxydar Seroxydar
Aluminium Sodium Silicate
Aluminium sodium silicate is an antacid with general properties similar to those of aluminium hydroxide. Aluminium silicate has been used similarly. They are also used as food additives.
Portugal: Acnoil Free.
France: Anti-H Cerat Inalterable Sulfuryl
Germany: Enelbin-Paste N Sulfredox
Hong Kong: Epilon
Basic Aluminium Carbonate
Basic aluminium carbonate is a combination of aluminium hydroxide and aluminium carbonate. It is an antacid with general properties similar to those of aluminium hydroxide (below). Basic aluminium carbonate has also been given orally as a phosphate binder in the treatment of hyperphosphataemia. For a discussion of the choice of phosphate binders, see Renal Osteodystrophy.
Dihydroxyaluminum Sodium Carbonate
Note. The name Carbaldrate (rINN) has been applied to (CH2AlNaO5,nH2O), a form of sodium (carbonato)dihydroxyaluminate(1-) hydrate.
Pharmacopoeias. In US.
The United States Pharmacopeia 31, 2008 (Dihydroxyaluminum Sodium Carbonate). A fine white odourless powder. It loses not more than 14.5% of its weight on drying. Practically insoluble in water and in organic solvents; soluble in dilute mineral acids with the evolution of carbon dioxide. A 4% suspension in water has a pH of 9.9 to 10.2. Store in airtight containers.
Dihydroxyaluminum sodium carbonate is an antacid with general properties similar to aluminium hydroxide that is given in doses of about 300 to 600 mg by mouth.
The United States Pharmacopeia 31, 2008: Dihydroxyaluminum Sodium Carbonate Tablets.
Poland: Alugastrin Gastrinal
Turkey: Dank Kompensan.