Alexitol Sodium
Drug Approvals
(British Approved Name, rINN)
Profile
Alexitol sodium is an antacid with general properties similar to those of aluminium hydroxide. It is given orally in doses of 360 to 720 mg when required, up to a maximum of sixteen 360-mg tablets in 24 hours.
Preparations
Proprietary Preparations
Hong Kong: Actal
Malaysia: Actal
Singapore: Actal
Thailand: Actal
UK: Actal.
Multi-ingredient
Malaysia: Actal Plus
Almagate
Drug Approvals
(British Approved Name, US Adopted Name, rINN)
Pharmacopoeias. In Europe.
European Pharmacopoeia, 6th ed. (Almagate). A white or almost white, fine crystalline powder. It contains 15.0 to 17.0% aluminium calculated as aluminium oxide, 36.0 to 40.0% magnesium calculated as magnesium oxide, and 12.5 to 14.5% carbonic acid calculated as carbon dioxide. Practically insoluble in water, in alcohol, and in dichloromethane. It dissolves with effervescence and heating in dilute mineral acids. The filtrate of a 4% suspension in water has a pH of 9.1 to 9.7. Store in airtight containers.
Profile
Almagate is a hydrated aluminium-magnesium hydroxycarbonate. It is an antacid with general properties similar to those of aluminium hydroxide and magnesium carbonate. It is given orally in doses of 1 to 1.5 g.
Proprietary Preparations
Mexico: Almax
Spain: Almax Deprece Obetine.
Almasilate
Drug Approvals
(British Approved Name, rINN)
International Nonproprietary Names (INNs) in main languages (French, Latin, and Spanish):
Profile
Almasilate is an artificial form of aluminium magnesium silicate hydrate. It is an antacid that is given orally in doses of up to about 1 g.
A hydrated native aluminium magnesium silicate is used as a suspending, thickening, and stabilising agent in pharmaceutical preparations. Attapulgite is another native form.
Preparations
Proprietary Preparations
Austria: Gelusil
Germany: Gelusil; Megalac; Simagel
Spain: Alubifar
Multi-ingredient
Austria: Gastripan
Germany: Gelusil-Lac; Neo-Pyodron N; Ultilac N
India: Entasid
Spain: Dolcopin
Switzerland: Gelusil N.
Aloglutamol
Drug Nomenclature
Profile
Aloglutamol has been used as an antacid.
Proprietary Preparations
Mexico: Sabro.
Hydrotalcite
Drug Nomenclature
Note. Compounded preparations of hydrotalcite may be represented by the following names:
- Co-simalcite x/y (BAN) — where x and y are the strengths in milligrams of simeticone and hydrotalcite respectively.
Pharmacopoeias. In British.
BP2008 (Hydrotalcite). A hydrated form of an aluminium magnesium basic carbonate corresponding to the formula Al2Mg6(OH)16CO3,4H2O. It contains not less than 15.3% and not more than 18.7% of Al2O3 and not less than 36.0% and not more than 44.0% of MgO. The ratio of Al2O3 to MgO is not less than 0.40 and not more than 0.45. A white or almost white, free-flowing, granular powder. Practically insoluble in water it dissolves in dilute mineral acids with slight effervescence. A 4% suspension in water has apH of 8.0 to 10.0.
Profile
Hydrotalcite is an antacid that is given in oral doses of up to about 1 g.
Preparations
BP 2008: Hydrotalcite Tablets.
Proprietary Preparations
Austria: Talcid; Talidat
Czech Republic: Rutacid; Talcid; Talidat
Germany: Ancid; Megalac; Talcid; Talidat
Greece: Talcid
Hungary: Talcid; Tisacid
Israel: Talcid
Malaysia: Swecon
Mexico: Talcid
The Netherlands: Talcid; Talidat; Ultacit
Poland: Malgacid; Rutacid; Talcid; Ulcetal
Portugal: Talidat
Russia: Rutacid; Talcid
South Africa: Altacite
Spain: Talcid
Turkey: Talcid
Venezuela: Baytalcid .
Multi-ingredient
Indonesia: Promag
Japan: Eki Cabe
Philippines: Sinneco
United Kingdom: Altacite Plus.
Magaldrate
Drug Approvals
(British Approved Name, US Adopted Name, rINN)
INNs in other languages (French, Latin, and Spanish):
Note. Magaldrate was formerly described as Aluminium Magnesium Hydroxide (AlMg2(OH)7 monohydrate, CAS — 1317-26-6).
Pharmacopoeias. In Europe and US.
European Pharmacopoeia, 6th ed. (Magaldrate). A combination of aluminium and magnesium hydroxides and sulfates. It contains the equivalent of 90 to 105% of Al5Mg10(OH)31(SO4)2, calculated with reference to the dried substance. A white or almost white crystalline powder. Practically insoluble in water and in alcohol soluble in dilute mineral acids. It loses between 10 and 20% of its weight on drying at 200° for 4 hours.
The United States Pharmacopeia 31, 2008 (Magaldrate). A combination of aluminium and magnesium hydroxides and sulfates. It contains the equivalent of 90 to 105% of Al5Mg10(OH)31(SO4)2, calculated on the dried basis. A white odourless crystalline powder. Insoluble in water and in alcohol soluble in dilute solutions of mineral acids. It loses between 10 and 20% of its weight on drying at 200° for 4 hours.
Profile
Magaldrate is an antacid that is given in oral doses of up to about 2 g.
Preparations
British Pharmacopoeia 2008: Magaldrate Oral Suspension
The United States Pharmacopeia 31, 2008: Magaldrate and Simethicone Oral Suspension; Magaldrate and Simethicone Tablets; Magaldrate Oral Suspension; Magaldrate Tablets.
Proprietary Preparations
Argentina: Riopan
Austria: Riopan
Belgium: Gastricalm Riopan
Brazil: Riopan
Czech Republic: Marax
France: Riopan
Germany: Gastripan Gastrostacl Glysan Hevert-Mag Magastron Marax Riopan Simaphil
Greece: Felfar Riopan
Italy: Gadral Magaltop Magralibi Riopan
Poland: Malugastrin
Portugal: Riopan
Russia: Magalphil
South Africa: Riopone
Spain: Bemolan Gastromol Magion Minoton
Switzerland: Riopan
USA: losopan Riopan
Venezuela: Cremag.
Multi-ingredient
Argentina: Aci-Tip Carbogasol Antiacido
Australia: Mylanta Heartburn Relief
Brazil: Riopan Plus
Chile: Aci-Tip Antiax
Hong Kong: Nilcid-MPS
India: Maglid pH4 Rolac Plus Ulgel
Indonesia: Asidrat Magalat Nudramag
Mexico: Nilcidf Riopan
Spain: Compagel
Turkey: Asidopan Plus Simelgat Plus
UK: Bisodol Extra Bisodol Heartburn Relief
USA: losopan Plus Lowsium Plus Riopan Plus
Venezuela: Cremalon.
Jennifer is a clinical pharmacologist. She helps doctors of all medical specialties choose medications. Jennifer consults about drug dosage, interactions, and side effects.