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Mucosal protectants

Last updated on October 6, 2021

Mucosal protectantsCytoprotective drugs (mucosal protectants) play a role in the management of peptic ulcer disease (below). They may be divided into:

  • Chelates or complexes, which coat the gastric mucosa preferentially at sites of ulceration by forming an adherent complex with proteins. Those described in mis site include sucralfate and tripotassium dicitratobismuthate (which also has an antibacterial role in regimens aimed at eradicating Helicobacter pylori)
  • Miscellaneous drugs include liquorice and its derivatives, such as carbenoxolone, which may act by stimulating the synthesis of protective mucus

Described in this site are

  • Benexate
  • Carbenoxolone
  • Cetraxate
  • Dosmalfate
  • Ebrotidine
  • Ecabet
  • Enoxolone Aluminium
  • Gefarnate
  • Irsogladine
  • Liquorice
  • Nocloprost
  • Ornoprostil
  • Plaunotol
  • Polaprezinc
  • Rebamipide
  • Sofalcone
  • Sucralfate
  • Sulglicotide
  • Teprenone
  • Tripotassium Dicitratobismuthate
  • Troxipide
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