Prokinetic tings stimulate the motility of the gastrointestinal tract. Gastrointestinal smooth muscle exhibits intrinsic motor activity which is modified by autonomic innervation, local reflexes, and gastrointestinal hormones. This activity produces peristaltic waves, which move the gut contents from stomach to anus, and segmentations, which encourage digestion. Prokinetic drugs may act at various points within this complex system to enhance gastrointestinal movement. Those described in mis site include metoclopramide, cisapride, and domperidone. Other tings with prokinetic properties include parasympathomimetics such as bethanechol or neostigmine, and the macrolide antibacterial erythromycin.
Described in this site are: