Dihydroergotamine

(British Approved Name, rINN) Drug Nomenclature International Nonproprietary Names (INNs) in main languages (French, Latin, Russian, and Spanish): Synonyms: Dihidroergotamina; Dihydroergotamiini; Dihydroergotamin; Dihydroergotaminum BAN: Dihydroergotamine INN: Dihydroergotamine [rINN (en)] INN: Dihidroergotamina [rINN (es)] INN: Dihydroergotamine [rINN (fr)] INN:…

Drug Welchol for Hypercholesterolemia

Brand Name Drug: Welchol Active Ingredient Drug: colesevelam hydrochloride Indication: For the reduction of elevated low-density lipoprotein cholesterol in patients with primary hypercholesterolemia, as an adjunct to diet and exercise Company Name: GelTex Pharmaceuticals, Inc. Availability: Approved by…

Antispasmodics

Antispasmodics are drugs used for their relaxant action on smooth muscle, either direct or through an antimuscarinic action on the parasympathetic innervation. They play a role in the management of gastrointestinal spasm and irritable bowel syndrome (below) as…

Treatment of IBS. 5-HT3 Antagonists and 5-HT4 Agonists

According to Birrer, 96% of serotonin is concentrated in the gastrointestinal tract. As a major neurotransmitter, it exerts an effect on gut smooth muscle in response to central and physical stimuli primarily via the 5-HT3 and 5-HT4 receptors,…