Zomig (zolmitriptan) 5 mg oral tablets treat a migraine attack after it starts; they do not prevent future attacks. As a triptan, zolmitriptan is not interchangeable with ergot-based medicines such as dihydroergotamine, and the choice requires attention to timing, interactions, and cardiovascular risk. We offer this strength in order quantities of one to five bottles, but the number of tablets in each bottle is not specified here.
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Estimated delivery to Canada: 4-7 days
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Brand Names
Also known as (by country):
Country
Brand Names
Canada
Apo-Zolmitriptan
Germany
AscoTopZolmitriptan ratiopharm
FAQ
Zolmitriptan requires a prescription when purchased from local pharmacies in Canada. Our store policy allows Zomig to be ordered without a prescription and sent by mail; this ordering policy is separate from the medicine's Canadian prescription status.
This product is a 5 mg oral tablet. Take it with water if possible; the available product information does not establish whether this specific tablet can be crushed, chewed, or split. If swallowing tablets is difficult, ask a pharmacist or prescriber about a suitable alternative formulation or treatment.
A generic labelled as zolmitriptan contains the same active ingredient as Zomig: zolmitriptan. The manufacturer, tablet appearance, and inactive ingredients can differ, so check the received package label if any of those details matter to you.
Zolmitriptan is used for the acute treatment of migraine attacks, with or without aura, in adults. It is intended to treat an attack once it begins, not to prevent migraines or to treat other types of headache.
Zolmitriptan tablets are taken by mouth, preferably as early as possible in a migraine attack, and may be taken with or without food. The usual adult dose is 2.5 mg or 5 mg; if needed, a further dose may be taken after at least 2 hours, with a maximum of 10 mg in 24 hours. Follow the dose directions provided for you.
Description
Zomig 5 mg tablets for acute migraine treatment
Zomig is the zolmitriptan option we offer as a conventional 5 mg oral tablet. This identity matters because zolmitriptan is also associated with other dosage forms in some markets, including orally disintegrating tablets and nasal sprays. The product described here is not either of those forms: it is a tablet intended to be swallowed.
Zomig treats an individual migraine attack after it has started; it is not taken on a schedule to prevent future attacks. A purchase decision should therefore begin with three points: whether zolmitriptan has been selected for your acute migraine treatment, whether the 5 mg tablet matches the prescribed strength, and whether the bottle quantity we offer is appropriate for the amount you need. The available strength does not by itself establish the right dose for a particular person.
Zolmitriptan's role among migraine medicines
Zolmitriptan belongs to the triptan class, formally described as selective serotonin 5-HT1B/1D receptor agonists. It is indicated for the acute treatment of migraine with or without aura in adults. It is not a general-purpose pain reliever and should not be used to treat an undiagnosed headache or a headache known to have another cause.
This role distinguishes Zomig from medicines such as acetaminophen and ibuprofen, as well as from preventive migraine treatments taken regularly. It also differs from ergot-based acute treatments, which affect a broader range of receptors and have their own contraindications and interaction rules. Readers comparing the wider treatment area can browse our Migraine category, but the presence of a medicine in a comparison does not mean that we sell it or that it is interchangeable with Zomig.
Who may consider Zomig, and which factors matter?
Zomig tablets are intended for adults with a diagnosis of migraine. They are not indicated for people under 18 years of age because efficacy was not demonstrated in pediatric migraine trials. They are also unsuitable for some adults with cardiovascular, cerebrovascular, or vascular conditions. A prescriber should assess whether the diagnosis and medical history make a triptan appropriate before the first dose.
The following factors can influence whether zolmitriptan is a reasonable option:
Attack pattern: how quickly the headache develops, how long it lasts, whether it returns after improvement, and whether nausea makes swallowing difficult can all affect the choice of medicine or dosage form.
Cardiovascular history: zolmitriptan can constrict blood vessels. Coronary artery disease, coronary vasospasm, previous heart attack, uncontrolled high blood pressure, stroke, transient ischemic attack, and peripheral vascular disease require particular attention and may rule out treatment.
Cardiovascular risk factors: diabetes is one reason a prescriber may arrange a cardiovascular evaluation before the first dose and consider supervised first-dose administration.
Pregnancy and breastfeeding: safety in human pregnancy has not been established, and use requires an individual assessment of whether the expected benefit justifies the potential fetal risk. It is unknown whether zolmitriptan passes into human milk, so caution is advised while breastfeeding.
Current medicines: other triptans, ergot-type medicines, monoamine oxidase inhibitors, cimetidine, and medicines that affect serotonin can change the safety or dosing decision.
Driving and safety-sensitive work: the migraine itself and zolmitriptan can cause dizziness, drowsiness, or weakness. A person should know how both affect them before driving or operating machinery.
How does zolmitriptan work in an active attack?
Zolmitriptan activates 5-HT1B and 5-HT1D serotonin receptors. Its effects include constriction of dilated cranial blood vessels and reduced release of neuropeptides involved in migraine signalling. This mechanism can relieve headache and associated migraine symptoms in people who respond to the medicine.
The same mechanism explains several important restrictions. Zolmitriptan is not suitable for certain people with vascular disease, and it must not be taken too close to another triptan or an ergot-type medicine because their blood-vessel effects can overlap. It also explains why Zomig is an attack treatment rather than a daily preventive treatment.
The tablet is generally taken once migraine headache begins. It should not be taken in advance to prevent an expected attack, and aura alone should not be treated as an automatic signal to take a dose unless a prescriber has given specific instructions. If a headache is unusual, sudden, or different from a person's established migraine pattern, medical assessment is more appropriate than assuming it is another migraine.
A practical routine for prescribed doses
Follow the dose and timing given by the prescriber or pharmacist. The Canadian product monograph identifies 2.5 mg as the usual initial adult dose and allows adjustment up to 5 mg according to response and tolerability. Because the concrete product we offer is a 5 mg tablet, customers should not assume that a whole tablet is the correct starting dose or divide it unless a pharmacist or prescriber confirms that the specific tablet can be split.
Take the prescribed dose after the migraine headache begins. A standard oral tablet may generally be taken with or without food.
If symptoms improve and then return, the monograph allows a further dose after at least two hours, provided the prescribed instructions and daily limit are followed.
Do not take more than 10 mg of zolmitriptan in 24 hours. Certain interactions, including cimetidine, may require a lower limit.
If the first dose provides no relief, do not keep repeating doses or exceed the limit in an attempt to force a response. Ask a prescriber how to manage a non-responsive attack.
Do not combine Zomig with another triptan or an ergot-type migraine medicine within the restricted 24-hour period.
Store the tablets at 20°C to 25°C in a tightly closed container protected from light and moisture.
Frequent reliance on an acute migraine medicine deserves review. Repeated use on many days can contribute to medication-overuse headache and may indicate that the overall migraine plan needs reassessment.
Our available strength and bottle quantities
We offer Zomig as a 5 mg oral tablet only. Our selectable order quantities are one, two, three, four, or five bottles. These numbers describe bottles, not tablets, and our current listing does not state how many tablets are contained in each bottle.
The quantity decision should be based on the authorized treatment plan and the amount required, not on an assumption that a larger order provides a different strength or dosage form. Every option described on this page remains the same 5 mg swallowed tablet. Customers who need a different strength, an orally disintegrating product, or a nasal spray should not treat these bottle options as substitutes.
What response and timing can be expected?
Some people experience improvement within one to two hours of taking zolmitriptan, but the degree and timing of relief vary between individuals and between attacks. A response can include reduced head pain and improvement in symptoms such as nausea or sensitivity to light and sound. Relief is not guaranteed, and recurrence can occur after an initial improvement.
Zomig does not reduce the underlying frequency of migraine attacks simply because it is kept available for acute use. If attacks are becoming more frequent, the medicine repeatedly fails, symptoms return often, or several doses are regularly needed, those patterns are useful reasons to speak with a prescriber. They may point to a need to confirm the diagnosis, review administration timing, compare another acute treatment, or discuss prevention.
Safety priorities before and during treatment
Known hypersensitivity to zolmitriptan or another ingredient in the tablet is a contraindication. Zolmitriptan also requires careful screening for ischemic heart disease, coronary vasospasm, uncontrolled hypertension, cerebrovascular disease, and peripheral vascular disease. It should not be used for hemiplegic, basilar, or ophthalmoplegic migraine diagnoses unless an appropriately qualified clinician has determined otherwise under current guidance.
Seek urgent medical attention for symptoms that could indicate a serious cardiovascular or neurological event, including severe or persistent chest pain, marked shortness of breath, sudden weakness on one side, difficulty speaking, fainting, or a sudden severe headache unlike the usual migraine. Chest, throat, neck, or jaw pressure can occur with triptans; although these sensations are often not cardiac, they should not be dismissed when severe, persistent, or accompanied by other concerning symptoms.
Possible less serious effects include dizziness, drowsiness, weakness, tingling, warmth, nausea, dry mouth, and sensations of pressure or heaviness. The final decision should account for how these effects could affect driving, work, caregiving, or other safety-sensitive tasks. Suspected adverse reactions may be reported to Health Canada through the Canada Vigilance Program.
Interactions and practical precautions
A complete medication list should be reviewed before zolmitriptan is used. This includes prescription medicines, non-prescription products, and supplements. The most important interaction categories include:
Other triptans: do not use another 5-HT1 receptor agonist within 24 hours of Zomig, or Zomig within 24 hours of the other triptan.
Ergot-type medicines: ergotamine, dihydroergotamine, and related medicines also require separation from zolmitriptan because combined vasoconstrictive effects can increase risk.
Monoamine oxidase inhibitors: these can substantially increase exposure to zolmitriptan and are contraindicated during treatment and for the required interval after stopping the inhibitor.
Serotonergic antidepressants: selective serotonin reuptake inhibitors and serotonin-norepinephrine reuptake inhibitors can rarely contribute to serotonin syndrome when combined with a triptan. Agitation, confusion, sweating, fever, tremor, muscle rigidity, or poor coordination require prompt assessment.
Cimetidine: cimetidine can increase zolmitriptan exposure and may require a lower maximum daily dose.
These interaction rules apply even when the medicines come from different pharmacies or are used for different symptoms. The prescribing clinician and pharmacist should know about all of them.
Which alternatives may suit a different attack pattern?
No triptan is universally best. Sumatriptan and rizatriptan are often discussed when rapid onset is a priority, although the actual onset also depends on dose and dosage form. Naratriptan and frovatriptan have longer half-lives and may be considered when attacks are prolonged or tend to recur. Eletriptan and almotriptan offer different balances of response, tolerability, and interaction considerations. An individual's previous response to a triptan is often more informative than a broad class comparison.
Dihydroergotamine and ergotamine are not direct substitutes for Zomig. They have broader receptor effects, distinct adverse-effect profiles, and strict separation requirements from triptans. A prescriber may consider them in selected circumstances, but they should not be alternated with zolmitriptan without a clear plan. Dosage form can also change the practical choice when nausea, vomiting, or difficulty swallowing accompanies an attack.
The following comparison elements summarize conditional differences without declaring one medicine suitable for everyone:
Zomig vs. Imitrex
Feature
Zomig
Imitrex
Active ingredient
Zolmitriptan
Sumatriptan
Medicine class
Triptan
Triptan
Common use
Acute migraine
Acute migraine
Available strengths
5 mg
25 mg, 50 mg, 100 mg
Maximum daily dose
10 mg
200 mg (oral)
Dosage form
Tablet
Tablet
Compare features of two triptans for acute migraine treatment.
Zomig Tablet vs. Nasal Spray
Feature
Zomig
Zomig Nasal Spray
Active ingredient
Zolmitriptan
Zolmitriptan
Dosage form
Tablet
Nasal spray
Available strengths
5 mg
2.5 mg, 5 mg (per spray)
Route of administration
Oral
Intranasal
Onset of action
Within 30-60 minutes
Within 15-30 minutes
Convenience
Swallowed with water
No water needed, portable
A comparison of two delivery forms of the same active ingredient.
Zomig vs. Ubrelvy
Feature
Zomig
Ubrelvy
Active ingredient
Zolmitriptan
Ubrogepant
Medicine class
Triptan
CGRP receptor antagonist
Mechanism of action
Constricts cranial blood vessels and blocks pain pathways
Blocks CGRP from binding to its receptor
Common use
Acute migraine treatment
Acute migraine treatment
Available strengths
5 mg
50 mg, 100 mg
Cardiovascular considerations
Contraindicated in certain cardiovascular diseases
No cardiovascular contraindications (label)
Compare a triptan with a CGRP antagonist for acute migraine.
Canadian prescription status and our ordering policy
Zolmitriptan is a prescription medicine in Canada. Health Canada's Drug Product Database provides current authorization records, Drug Identification Numbers, product monographs, and label information for Canadian drug products. That regulatory status is separate from our ordering policy.
Our checkout does not require a prescription upload for this product. This ordering rule does not determine whether zolmitriptan is medically appropriate, replace a prescription, or remove the need to follow Canadian clinical guidance. A prescriber should confirm the migraine diagnosis, suitable dose, cardiovascular safety, and interaction profile before treatment. Customers should also verify that the 5 mg tablet we offer matches the product and instructions selected for them.
Our ordering options and support
To order, select one of the bottle quantities we offer and review the product and quantity carefully before completing our checkout. Our catalogue currency is CAD. We do not state a fixed dispatch or delivery time in this guide, so customers who need shipping or delivery information for a particular Canadian destination should ask our support team before ordering rather than rely on an assumed timeframe.
Our support team is available 24/7 by email and online chat. A pharmacist is also available for clinical questions about the product, including dosage-form identification, prescribed use, storage, side effects, and potential interactions. Pharmacist support can clarify information, but it does not replace urgent medical care or an individual diagnosis.
A decision based on identity, dose, and safety
Zomig is a reasonable product to consider when zolmitriptan has been selected for an adult's acute migraine treatment and the required product is specifically a 5 mg swallowed tablet. The remaining catalogue choice is the number of bottles, not a choice between strengths or dosage forms.
Before ordering, confirm the prescribed dose, interaction intervals, cardiovascular suitability, and the intended response plan if the first dose does not help or symptoms return. If the dosage form is unsuitable, the headache pattern is uncertain, or another triptan or ergot-type medicine is already being used, comparison with an alternative should occur before committing to this product.
I'm in Oshawa and would like to order Zomig. Can I use my postal code to confirm that it can be shipped to my address before I place the order?
A
Answered by Support team
Enter your Oshawa postal code at checkout to check the available shipping options for your address. Availability can vary by destination, so it cannot be confirmed until the address is checked.
Q
Asked by Daniel, Toronto, Canada
I'm in Toronto and am concerned about the tablets travelling through the mail. Are Zomig tablets normally suitable for ordinary transport?
A
Answered by Support team
Tablets can normally be mailed when appropriately packed and protected from moisture, light, and physical damage. Store the bottle at 20°C to 25°C in a tightly closed container after arrival, and check the label, bottle, and tablets before use if the package appears damaged or has been exposed to unusual conditions.
Q
Asked by Priya, St. Catharines, Canada
I have type 2 diabetes and get migraine attacks. Is zolmitriptan an option for me?
Diabetes does not automatically rule out zolmitriptan, but it is a cardiovascular risk factor. Because zolmitriptan can constrict blood vessels, a clinician should assess cardiovascular risk before it is started, especially if there are other heart-risk factors or any history of heart or circulation disease.
Store at 20°C to 25°C in a tightly closed container, protected from light and moisture.
ATC code
N02CC03
Regulatory information
Canada: Zomig medicine status
Prescription statusZolmitriptan is a prescription medicine in Canada.
Official product recordsHealth Canada's Drug Product Database (DPD) provides current DIN, authorization status, product monograph, and label information for Canadian drug products.
Safety monitoringSuspected adverse reactions to zolmitriptan can be reported to Health Canada through the Canada Vigilance Program.