Lopressor (Metoprolol) Oral Tablets

Lopressor
Generic:
Metoprolol
Indications:
angina heart attack hypertension
Analogs:
Metoprolol Toprol XL Atenolol Bisoprolol Nebivolol Carvedilol Lisinopril Losartan Amlodipine Hydrochlorothiazide Tenormin Zebeta Coreg Bystolic Propranolol Inderal
Lopressor is an immediate-release oral metoprolol tablet available from us in 12.5 mg, 25 mg, 50 mg, and 100 mg strengths. This guide walks through how the medicine works, what a typical routine looks like, how it compares with other beta blockers, and what to expect when ordering a package through our Canadian catalogue.
In stock: 10 packs
AdultsPregnancyAllergiesDiabetesBreastfeedingChildrenDriving

Dosages

Lopressor 12.5 mg

Quantity Price per tablet You save Total price
60 C$1.29 - C$77.18
120 C$1.09 C$23.94 C$130.42
240 C$1.03 C$60.84 C$247.87
360 C$0.96 C$118.59 C$344.49

Lopressor 25 mg

Quantity Price per tablet You save Total price
60 C$0.94 - C$56.62
90 C$0.74 C$18.45 C$66.48
120 C$0.65 C$35.63 C$77.60
180 C$0.54 C$72.95 C$96.90

Lopressor 50 mg

Quantity Price per tablet You save Total price
90 C$0.73 - C$65.77
120 C$0.64 C$11.08 C$76.62
180 C$0.57 C$28.87 C$102.67
270 C$0.52 C$57.18 C$140.13
360 C$0.49 C$86.47 C$176.61

Lopressor 100 mg

Quantity Price per tablet You save Total price
60 C$1.27 - C$75.91
90 C$1.06 C$18.38 C$95.49
120 C$0.97 C$35.35 C$116.47
180 C$0.86 C$72.81 C$154.92
270 C$0.81 C$123.87 C$217.73
360 C$0.77 C$176.75 C$278.72

Manufacturers

ApotexAstraZenecaGenPharma International Pvt. Ltd.HexalIntas Pharmaceuticals Ltd.NovartisRecordatiRecordati PharmaSun Pharmaceutical Industries Ltd.Validus Pharmaceuticals

Payment & Shipping

Package Example

Your order is carefully packed and ships within 24 hours. Here's the typical package.

Sized like a regular personal letter (24x11x0.7 cm), with no indication of its contents.

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Back View
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Shipping Times
Shipping MethodEstimated delivery
Express Free for orders over C$422.51Estimated delivery to Canada: 4-7 days
Standard Free for orders over C$281.68Estimated delivery to Canada: 14-21 days
EMSCanada Post
Payment Methods
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Discount Coupons

  • Victoria Day - May 18, 2026 8% VICTORIA8
  • Canada Day - July 1, 2026 10% CANADADAY10
  • Labour Day - September 7, 2026 6% LABOUR6
  • Thanksgiving (Canada) - October 12, 2026 9% THANKS9
  • Boxing Day - December 26, 2026 12% BOXING12

Brand Names

Also known as (by country):
CountryBrand Names
Canada
Apo-Metoprolol Lopresor
United States
Toprol-XL
United Kingdom
Betaloc Lopresor
France
Seloken
Australia
Betaloc
New Zealand
Betaloc Lopresor Slow-Lopresor
Germany
Beloc-ZOK Metohexal
Italy
Lopresor Seloken
Belgium
Lopresor Selo-Zok Seloken Slow-Lopresor

FAQ

A prescription is required to buy metoprolol from local pharmacies in Canada. Our store policy allows you to order these tablets without a prescription and have them sent by mail.

Alcohol is best avoided while taking metoprolol. It can add to blood-pressure-lowering effects and increase dizziness, light-headedness, or fainting risk, especially when treatment is started or the dose changes.

During pregnancy, metoprolol should be used only after a clinician has weighed the expected benefit against potential fetal and newborn risks, including slow heart rate, low blood pressure, and low blood sugar. Metoprolol passes into breast milk, so breastfeeding requires caution and observation of the infant for possible beta-blocker effects such as unusual sleepiness, poor feeding, slow heart rate, or low blood sugar.

Description

Lopressor tablets contain metoprolol tartrate, an immediate-release formulation. That distinction is the most practical thing to understand before comparing options: extended-release metoprolol succinate products, sold under names such as Toprol XL, release the medicine differently and are not interchangeable with Lopressor without a prescriber adjusting the regimen. Depending on the indication, dose, and individual treatment plan, immediate-release metoprolol may be prescribed once daily or in divided doses. We sell the immediate-release tablet in 12.5 mg, 25 mg, 50 mg, and 100 mg strengths, with package sizes that support a range of prescribed schedules and supply lengths.

This guide is written to help someone who is comparing Lopressor against other beta blockers, or deciding whether to order our 12.5 mg, 25 mg, 50 mg, or 100 mg tablets, understand what the medicine does, how a routine with it typically looks, what matters for safety, and what ordering and delivery look like through our site.

What Lopressor Is and How It Fits into Heart and Blood Pressure Care

Metoprolol belongs to the beta blocker class, and more specifically it is a cardioselective (beta-1 selective) beta blocker, identified by the ATC code C07AB02. Oral metoprolol tartrate is established for managing hypertension, for reducing the frequency of angina attacks, and for use after a heart attack, where it has been shown to lower the risk of further cardiac events. Each of these uses rests on the same underlying action: slowing and softening the heart's response to adrenaline-type signals.

Because Lopressor is the immediate-release tartrate salt, its effect rises and falls more quickly than that of extended-release succinate products. Its dosing schedule may therefore use once-daily or divided doses, depending on the indication and prescribed total daily dose, rather than the once-daily schedule commonly used with extended-release metoprolol. Keeping this distinction in mind matters most when someone is switching between an immediate-release and an extended-release product, since the total daily dose, release pattern, and dosing interval should not be changed without a prescriber adjusting the regimen.

Who Might Consider Lopressor, and What Should Guide That Decision?

Metoprolol tablets are generally considered for adults managing high blood pressure, angina, or recovery after a heart attack, usually alongside lifestyle measures or other heart medicines. A few practical factors tend to influence whether Lopressor specifically, rather than another beta blocker, fits someone's situation:

  • A preference or clinical reason for a shorter-acting, more titratable immediate-release tablet rather than a once-daily extended-release product.
  • An existing prescription written specifically for metoprolol tartrate, which this tablet matches, rather than metoprolol succinate.
  • A need for one of our available strengths, from the lower 12.5 mg tablet, which may support gradual titration or a lower prescribed dose, up to the 100 mg tablet for regimens requiring that strength.
  • Coexisting conditions such as diabetes or asthma-type airway disease, which do not necessarily rule out metoprolol because of its cardioselectivity, but which still warrant medical input.

People who are pregnant, breastfeeding, living with diabetes, or caring for a child are not automatically excluded from metoprolol use, but each of those situations calls for individual medical judgment rather than a one-size-fits-all answer, which is why we keep that guidance in our regulatory and safety information rather than repeating it here in full. If blood pressure management more broadly is what brought you here, our Blood Pressure category outlines other treatment options worth comparing alongside Lopressor.

How Does Metoprolol Work, and What Does That Mean Day to Day?

Metoprolol blocks beta-1 adrenergic receptors, which are concentrated in heart tissue. By dampening the heart's response to adrenaline and noradrenaline, it reduces heart rate, eases the force of each contraction, and lowers the heart's oxygen demand. It also reduces renin release from the kidneys, which contributes to its blood-pressure-lowering effect over time.

How Lopressor Works in the Body
In practical terms, this translates into a heart that beats a little slower and works a little less hard, which is beneficial for someone with hypertension or angina but is also the reason beta blockers cause some of their most common side effects, such as fatigue, cold hands and feet, or a noticeably lower resting pulse.

Because the immediate-release tablet's effect builds and fades more quickly than an extended-release version, some people may notice changes in heart rate, blood pressure, or side effects around dosing times, particularly during the first days of treatment or after a dose change.

Building a Daily Routine Around Lopressor

Metoprolol tartrate tablets are generally taken with or immediately after meals. Taking each dose consistently in the same relationship to food helps keep absorption more predictable and may reduce the mild stomach upset some people notice. A prescriber may start at a lower total daily dose and increase it gradually over days to weeks, depending on the condition being treated, while watching blood pressure, heart rate, and symptoms at each step. Our range from 12.5 mg to 100 mg provides several strength options for a prescribed regimen.

A few habits make an immediate-release regimen easier to manage:

  • Taking each dose at the prescribed time and maintaining a consistent routine, especially when the daily amount is divided between two or more doses.
  • Following the product instructions or a clinician's advice for a missed dose; in general, a missed dose should not be doubled to make up for the omission.
  • Checking resting pulse periodically if advised, especially after a dose increase, since an unusually slow heart rate is one of the clearest early signs that a dose may need review.
  • Never stopping metoprolol abruptly after regular use, because sudden withdrawal can trigger rebound increases in heart rate and blood pressure and, in people with underlying heart disease, can provoke angina or more serious cardiac events.

Strengths and Package Sizes We Offer

We currently list Lopressor tablets in 12.5 mg, 25 mg, 50 mg, and 100 mg strengths, sold by the pill. Package sizes vary by strength to support different prescribed regimens and supply lengths: the 12.5 mg tablet is available in packs of 60, 120, 240, or 360 pills; the 25 mg tablet in packs of 60, 90, 120, or 180; the 50 mg tablet in packs of 90, 120, 180, 270, or 360; and the 100 mg tablet in packs of 60, 90, 120, 180, 270, or 360. This spread lets someone choose a smaller supply during titration or a larger supply for an established regimen, depending on the prescribed dosing frequency. Exact current pricing, in-stock packs, and payment details for each strength are shown on the ordering panel for this page rather than repeated in this guide.

What to Expect, and When

Metoprolol's effect on heart rate can appear within an hour or two of an oral dose, with its blood-pressure-lowering benefit developing through consistent use. The response to treatment is usually assessed over the following days and weeks, particularly after the person has spent time on a stable dose, which is part of why dose changes are not normally made from day to day. For angina, many people notice fewer or milder episodes once an effective dose is reached; for hypertension, the main marker of success is a lower blood pressure reading over time rather than any particular feeling, since high blood pressure itself is often symptomless.

Important Safety Priorities Before You Start

Metoprolol is not suitable for everyone. It is contraindicated in people with certain slow heart rhythms or conduction disorders, cardiogenic shock or overt cardiac failure that has not been stabilized, very low blood pressure, or a known hypersensitivity to metoprolol or a product ingredient. Because it can cause dizziness, fatigue, or reduced alertness, especially when starting treatment or after a dose increase, driving or operating machinery should be approached cautiously until the body's response to a new dose is known. The most frequently reported effects include tiredness, dizziness, cold extremities, and a slower resting pulse; less commonly, people notice shortness of breath, mood changes, or sleep disturbance. Anyone with asthma or significant airway disease should discuss beta blocker use with a prescriber, since even cardioselective agents like metoprolol can affect airway tone in some people, particularly at higher doses.

What Interacts with Lopressor, and What Else Should You Watch For?

Metoprolol is metabolized mainly through the CYP2D6 liver enzyme pathway, so medicines that strongly inhibit that enzyme, including certain antidepressants and antiarrhythmics, can raise metoprolol levels and intensify its effects. Combining metoprolol with other heart-rate-lowering medicines, such as calcium channel blockers like verapamil or diltiazem, certain antiarrhythmics, or digoxin, needs careful medical oversight because the combined effect on heart rate and conduction can become excessive. Metoprolol is also frequently combined, under medical supervision, with other blood-pressure-lowering agents, including diuretics such as Hydrochlorothiazide, when a single agent does not bring blood pressure to target. Alcohol can add to metoprolol's blood-pressure-lowering and sedative effects, and anyone with diabetes should be aware that metoprolol can blunt some of the usual warning signs of low blood sugar, such as a racing heart, making routine glucose monitoring more important.

Lopressor Compared with Atenolol and Bisoprolol

Lopressor is one of several cardioselective beta blockers used for similar cardiovascular purposes, and the differences between them tend to matter more in practice than their shared drug class suggests.

Key Differences: Lopressor vs. Atenolol

FeatureLopressorAtenolol
Active ingredientMetoprololAtenolol
Pharmacological classCardioselective beta-1 blockerCardioselective beta-1 blocker
Primary indicationsHypertension, angina, post-myocardial infarctionHypertension, angina, post-myocardial infarction
Dosage formTabletTablet
Available strengths12.5 mg, 25 mg, 50 mg, 100 mg25 mg, 50 mg, 100 mg
Primary eliminationHepatic metabolismRenal excretion
Both are cardioselective beta blockers used for cardiovascular conditions, differing in elimination and dosing profiles.
Atenolol is cleared mainly by the kidneys rather than the liver, which matters for people with reduced kidney function, and it is commonly dosed once daily. Lopressor is an immediate-release metoprolol product whose schedule may use once-daily or divided doses according to the indication and prescribed regimen.

Key Differences: Lopressor vs. Bisoprolol

FeatureLopressorBisoprolol
Active ingredientMetoprololBisoprolol
Pharmacological classCardioselective beta-1 blockerHighly selective beta-1 blocker
Common indicationsHypertension, angina, heart attack recoveryHypertension, stable chronic heart failure
Dosage formTabletTablet
Available strengths12.5 mg, 25 mg, 50 mg, 100 mg2.5 mg, 5 mg, 10 mg
Typical dosing scheduleOften divided across the dayUsually taken once daily
Comparison of two cardioselective beta blockers commonly prescribed for hypertension management.
Bisoprolol is highly beta-1 selective with a longer half-life that supports once-daily dosing for many people, while Lopressor's shorter-acting tartrate formulation may be selected when an immediate-release metoprolol regimen is appropriate. None of these differences make one option universally better; they simply shift which practical factors, such as kidney function, dosing convenience, clinical experience, and the need for dose adjustment, matter most for a given person.

Accessing Lopressor in Canada: Prescription Status and Our Ordering Policy

Metoprolol is authorised for human medicinal use in Canada, and metoprolol tablets are classified as a prescription medicine under Canadian regulation. That classification describes the medicine's legal status, separate from how we process an order on our site. Our own ordering policy does not require you to submit a prescription before we accept an order for Lopressor, so you can order Lopressor without a prescription through our catalogue. We still recommend treating ongoing beta blocker use as something a clinician should be aware of, since starting, stopping, or adjusting metoprolol is safest with periodic blood pressure and heart rate checks.

Ordering, Delivery, and Receiving Your Lopressor Order

We have operated as an online pharmacy catalogue since 2018, and our support team is reachable 24/7 by email or online chat, including access to a pharmacist for product questions. Ordering follows a straightforward sequence:

  • Choose your Lopressor strength (12.5 mg, 25 mg, 50 mg, or 100 mg) and preferred pack size from the quantities we currently list for that strength.
  • Complete checkout in Canadian dollars using our available payment methods, without needing to upload a prescription first.
  • Receive order confirmation and tracking details once your package is prepared for dispatch.
  • Expect delivery within our estimated shipping window for your address in Canada, with packing designed to protect tablets from moisture and temperature extremes in transit.

Once your tablets arrive, store them at 20°C to 25°C in a tightly closed, light-resistant container, away from moisture, which keeps the medicine stable until its labelled expiry.

Is Lopressor the Right Choice for You?

Lopressor makes the most sense for someone whose treatment plan specifically calls for immediate-release metoprolol tartrate and who can follow the prescribed dosing schedule, whether it uses one dose or divided doses. Our 12.5 mg, 25 mg, 50 mg, and 100 mg strengths provide options for different prescribed regimens. If a consistently once-daily routine or a different elimination profile matters more, the comparisons above with atenolol and bisoprolol are worth weighing before you decide. Whichever beta blocker suits your situation, pairing it with regular blood pressure and heart rate checks, consistent dosing habits, and open communication with a prescriber remains the foundation of safe, effective long-term use, and our team is available if you have questions about strengths, packaging, or your order before you check out.

Medically reviewed by
Lynette Ellis
Pharmacist
Updated November 7, 2026

Product specifications

Active ingredientMetoprolol
Drug classBeta blocker
Dosage formTablet
Available strengths12.5 mg, 25 mg, 50 mg, 100 mg
Route of administrationOral
StorageStore at 20°C to 25°C in a tightly closed, light-resistant container, and protect from moisture.
ATC codeC07AB02

Regulatory information

Authorization StatusMetoprolol is approved for human therapeutic use in Canada.
Prescription StatusMetoprolol tablets are classified as a prescription medication and require a valid prescription from a licensed practitioner.

More information