Lopressor (Metoprolol) Tablets

Lopressor
Generic:
Metoprolol
Indications:
angina heart attack hypertension
Analogs:
Metoprolol Toprol XL Atenolol Bisoprolol Nebivolol Carvedilol Lisinopril Losartan Amlodipine Hydrochlorothiazide Tenormin Zebeta Coreg Bystolic Propranolol Inderal
Lopressor supplies metoprolol tartrate as an immediate-release oral tablet in four strengths, packaged in several quantities so customers can match the prescribed treatment supply to an ongoing cardiovascular routine.
In stock: 10 packs
AdultsPregnancyAllergiesDiabetesBreastfeedingChildrenDriving

Dosages

Lopressor 12.5 mg

Quantity Price per tablet You save Total price
60 $0.91 - $54.80
120 $0.77 $17.00 $92.60
240 $0.73 $43.20 $176.00
360 $0.68 $84.20 $244.60

Lopressor 25 mg

Quantity Price per tablet You save Total price
60 $0.67 - $40.20
90 $0.52 $13.10 $47.20
120 $0.46 $25.30 $55.10
180 $0.38 $51.80 $68.80

Lopressor 50 mg

Quantity Price per tablet You save Total price
90 $0.52 - $46.70
120 $0.45 $7.87 $54.40
180 $0.41 $20.50 $72.90
270 $0.37 $40.60 $99.50
360 $0.35 $61.40 $125.40

Lopressor 100 mg

Quantity Price per tablet You save Total price
60 $0.90 - $53.90
90 $0.75 $13.05 $67.80
120 $0.69 $25.10 $82.70
180 $0.61 $51.70 $110.00
270 $0.57 $87.95 $154.60
360 $0.55 $125.50 $197.90

Manufacturers

ApotexAstraZenecaGenPharma International Pvt. Ltd.HexalIntas Pharmaceuticals Ltd.NovartisRecordatiRecordati PharmaSun Pharmaceutical Industries Ltd.Validus Pharmaceuticals

Payment & Shipping

Package Example

Your order is carefully packed and ships within 24 hours. Here's the typical package.

Sized like a regular personal letter (9.4x4.3x0.3 inches), with no indication of its contents.

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Shipping Times
Shipping MethodEstimated delivery
Express Free for orders over $300.00Estimated delivery to the U.S.: 4-7 days
Standard Free for orders over $200.00Estimated delivery to the U.S.: 14-21 days
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Discount Coupons

  • Independence Day - July 4, 2026 10% JULY410
  • Labor Day - September 7, 2026 7% LABOR07
  • Thanksgiving - November 26, 2026 9% THANKS09

Brand Names

Also known as (by country):
CountryBrand Names
United States
Toprol-XL
United Kingdom
Betaloc Lopresor
Canada
Apo-Metoprolol Lopresor
Australia
Betaloc
New Zealand
Betaloc Lopresor Slow-Lopresor

FAQ

Metoprolol can cause dizziness, tiredness, or reduced alertness, particularly when treatment starts or the dose changes. Do not drive or operate machinery if it affects your alertness, vision, or coordination.

Metoprolol is a beta blocker used to treat high blood pressure and angina and may be used after a heart attack. Depending on the formulation and clinical situation, it may also be prescribed for certain heart rhythm disorders or heart failure.

Description

If you are comparing beta blockers, the detail that matters most about Lopressor is its release profile: these are immediate-release metoprolol tartrate tablets, not the extended-release metoprolol succinate found in products like Toprol XL. That distinction changes how often the medicine is taken, how a missed dose behaves, and how closely blood pressure and heart rate need to be tracked between doses. We offer Lopressor in 12.5 mg, 25 mg, 50 mg, and 100 mg tablets across several package sizes, which lets a returning customer line up a refill with an existing prescription rather than guess at an unfamiliar strength.

Lopressor at a Glance: The Distinction That Matters

Because Lopressor is immediate-release, metoprolol tartrate reaches the bloodstream relatively quickly and clears faster than the succinate form. Depending on the indication, dose, and individual response, a prescriber may direct it to be taken once daily or in divided doses rather than treat it as interchangeable with a once-daily extended-release product. For someone switching from another beta blocker, or comparing a divided-dose tablet against a once-daily extended-release option, that dosing rhythm is often the deciding factor. We keep our strengths and package quantities aligned with that immediate-release identity so the product you add to your cart matches what a prescriber actually wrote for.

What Lopressor Is and Why We Carry It

Metoprolol belongs to the beta blocker class, and more specifically it is a beta-1 selective (cardioselective) agent, meaning it acts preferentially on the beta-1 receptors concentrated in heart tissue rather than the beta-2 receptors found in the lungs and blood vessels. Oral metoprolol tartrate is established for:

  • Hypertension, used alone or alongside other blood pressure medicines
  • Angina pectoris, to reduce the frequency and severity of chest pain episodes
  • Early treatment following a heart attack, to help stabilize cardiac workload

We carry Lopressor because these are core, well-documented cardiovascular uses, and the tablet form gives customers a familiar, flexible way to fill a prescription that calls for metoprolol tartrate specifically rather than a combination product or the succinate salt.

Who Typically Considers Lopressor

Adults being treated for high blood pressure, angina, or recovering from a cardiac event are the usual candidates, generally under the direction of a physician who has reviewed their heart rate, blood pressure pattern, and other health conditions. A few practical factors tend to shape the decision between Lopressor and an alternative: how consistently someone can follow the prescribed dosing schedule, whether they have asthma or diabetes that calls for closer monitoring, whether they are pregnant, and whether dizziness from treatment initiation could affect driving or operating machinery. Customers managing hypertension as part of a broader regimen may also want to browse our blood pressure options to see how Lopressor fits alongside other medicines they may already be taking.

How Metoprolol Works in the Body

Metoprolol blocks beta-1 adrenergic receptors in the heart, which reduces the influence of adrenaline-driven signals that would otherwise speed up the heart rate and increase the force of each contraction. The practical result is a heart that beats more slowly and with less force, lowering the oxygen demand of heart muscle and easing the pressure exerted on artery walls. It also dampens renin release from the kidneys, which contributes further to blood pressure control over time.

How Lopressor Works in the Body

Seeing that sequence laid out helps explain why metoprolol is not a fast-acting painkiller for chest discomfort, but rather a medicine that recalibrates how hard the heart has to work, hour after hour, as long as it is taken consistently.

Building a Daily Routine With Lopressor

Because Lopressor is immediate-release, it works best on a steady schedule. It may be prescribed once daily or in divided doses depending on the indication, total daily dose, and individual response. Taking it at the same times each day and consistently with or immediately after meals helps maintain a predictable effect and may reduce variation in absorption. Tablets are swallowed with a glass of water; they should not be split or crushed unless a prescriber or pharmacist confirms that the specific tablet can be handled that way. Dose strength and frequency are adjusted gradually by a prescriber based on heart rate and blood pressure response, which is why we offer four strengths rather than a single fixed dose. One routine point deserves particular attention: metoprolol should never be stopped abruptly. Sudden discontinuation can trigger rebound increases in heart rate and blood pressure, and in people with underlying coronary disease it has been associated with worsening chest pain or even a heart attack. Any change in dose or a decision to stop should be tapered under medical guidance.

Strengths and Package Sizes We Offer

We stock Lopressor tablets in the following strengths, each available in multiple pill counts so a customer can match the pack size to the expected treatment supply:

  • 12.5 mg tablets in packs of 60, 120, 240, or 360 pills
  • 25 mg tablets in packs of 60, 90, 120, or 180 pills
  • 50 mg tablets in packs of 90, 120, 180, 270, or 360 pills
  • 100 mg tablets in packs of 60, 90, 120, 180, 270, or 360 pills

Because some regimens use divided daily doses, larger pack sizes are often practical for ongoing hypertension or angina management, while a smaller pack can suit someone early in treatment whose dose may still be adjusted.

What to Expect and When

Some reduction in heart rate and blood pressure can appear within hours of the first doses, but the fuller blood pressure effect generally builds over one to two weeks of consistent use as the body adjusts. For angina, many people notice fewer or milder episodes during the first weeks of treatment, though the medicine works best as a steady preventive measure rather than something taken only when chest discomfort starts. After a heart attack, the treatment duration is determined by the prescriber based on the clinical situation and ongoing response; it should not be stopped or assigned an endpoint independently. Periodic check-ins to review heart rate, blood pressure, and overall response are a normal part of treatment.

Safety Priorities Before You Start

Metoprolol is not appropriate for everyone, and a few safety points deserve attention before starting or continuing treatment:

  • It is contraindicated in severe bradycardia, higher-degree heart block or sick sinus syndrome without a functioning pacemaker, cardiogenic shock, and decompensated heart failure.
  • People with severe peripheral circulation problems require particular caution because beta blockers can aggravate symptoms of reduced arterial circulation.
  • People with asthma or COPD should use it cautiously, since even beta-1 selective agents can provoke airway narrowing at higher doses.
  • People with diabetes should be aware that metoprolol can blunt the usual warning signs of low blood sugar, particularly a racing heartbeat, so blood sugar monitoring becomes more important.
  • Pregnant patients should only use metoprolol when a prescriber judges the benefit to outweigh the risk, since beta-blocker exposure later in pregnancy has been linked to slowed fetal heart rate and low blood sugar in newborns.
  • Dizziness, fatigue, or lightheadedness can occur, especially when treatment starts or a dose increases, which may affect driving or operating machinery until the response is known.

None of these points replace a prescriber's individualized assessment, but they outline the categories of risk that make metoprolol a prescription medicine rather than a casual over-the-counter choice.

Interactions and Practical Precautions

Metoprolol can interact with several other medicines and everyday substances. Combining it with calcium channel blockers such as verapamil or diltiazem can excessively slow the heart or worsen heart block, and stacking it with other beta blockers is generally avoided since the effects simply add up without added benefit. Other blood pressure medicines, including thiazide diuretics such as Hydrochlorothiazide, are commonly prescribed alongside metoprolol for hypertension, but the combined blood-pressure-lowering effect means dosing needs to be coordinated by a prescriber rather than adjusted independently. Clonidine requires particular caution: stopping clonidine while still taking a beta blocker like metoprolol can cause a dangerous rebound rise in blood pressure, so any clonidine taper is managed carefully around metoprolol use. NSAIDs can blunt metoprolol's blood-pressure-lowering effect over time, while certain antidepressants and antiarrhythmics that inhibit the CYP2D6 liver enzyme, such as fluoxetine, paroxetine, or quinidine, can raise metoprolol levels in the blood. Alcohol can intensify dizziness and should be used cautiously, especially early in treatment.

Comparing Lopressor With Other Beta Blockers

Lopressor is one of several beta blockers used for similar cardiovascular goals, and the right choice often comes down to dosing frequency, receptor selectivity, and how the body clears the drug. The comparisons below focus on distinctions that matter when deciding between Lopressor and a therapeutic alternative.

How Does Lopressor Compare to Tenormin?

Tenormin (atenolol) is another beta-1 selective beta blocker, but it is cleared mainly by the kidneys rather than the liver, which matters for people with reduced kidney function. Lopressor's hepatic metabolism, by contrast, makes liver function more relevant to its dosing.

How Does Lopressor Compare to Tenormin?

FeatureLopressorTenormin
Active ingredientMetoprolol tartrateAtenolol
Medication classCardioselective beta blockerCardioselective beta blocker
Common usesHypertension, angina, heart attack managementHypertension, angina, heart attack recovery
Dosage formTabletTablet
Available strengths12.5 mg, 25 mg, 50 mg, 100 mg25 mg, 50 mg, 100 mg
Metabolic clearancePrimarily metabolized by the liverPrimarily eliminated unchanged by the kidneys
Comparison of two cardioselective beta blockers with distinct elimination routes.

How Does Lopressor Compare to Toprol-XL?

Toprol-XL is the extended-release metoprolol succinate formulation, built for once-daily dosing and a smoother blood-level curve, while Lopressor's immediate-release tartrate form may require divided daily doses and is prescribed according to the indication and individual response.

How Does Lopressor Compare to Toprol-XL?

FeatureLopressorToprol-XL
Active ingredient (salt)Metoprolol tartrateMetoprolol succinate
Release profileImmediate releaseExtended release
Dosage formTabletTablet
Primary usesHypertension, angina, heart attack recoveryHypertension, angina, heart failure
Available strengths12.5 mg, 25 mg, 50 mg, 100 mg25 mg, 50 mg, 100 mg, 200 mg
Typical scheduleOften taken in multiple daily doses with mealsDesigned for once-daily dosing
Comparison of immediate-release and extended-release metoprolol formulations.

How Does Lopressor Compare to Zebeta?

Zebeta (bisoprolol) is also beta-1 selective and, like Lopressor, is taken as a standard tablet, but it has a longer half-life that typically supports once-daily use, an option worth weighing against Lopressor regimens that require more frequent dosing.

How Does Lopressor Compare to Zebeta?

FeatureLopressorZebeta
Active ingredientMetoprolol tartrateBisoprolol fumarate
Medication classCardioselective beta blockerCardioselective beta blocker
Common usesHypertension, angina, heart attack managementManagement of hypertension
Dosage formTabletTablet
Available strengths12.5 mg, 25 mg, 50 mg, 100 mg5 mg, 10 mg
Action profileShorter duration of actionLonger duration of action
Comparison of two beta-1-selective beta blockers used for cardiovascular control.

None of these alternatives are identical substitutes; switching between them involves a dosing conversion that a prescriber manages, since milligram-for-milligram equivalence does not carry across different beta blockers.

Prescription Status and Access in the United States

Metoprolol is authorized for human medicinal use in the United States, and Lopressor tablets are classified as a prescription medicine here, meaning treatment is ordinarily directed by a licensed prescriber. Our ordering policy does not require you to submit a prescription document before we accept your order, and we do not ask you to upload one at checkout. This is a detail about how we accept orders, not a change to metoprolol's underlying prescription classification, and we think it is worth keeping those two facts distinct when you are deciding where to order from.

Ordering, Delivery, and Receiving Your Lopressor

We have operated PocketDrugGuide since 2018, and our team is reachable 24/7 by email or online chat, with a pharmacist available to answer questions about dosing, interactions, or anything else that comes up while you are deciding between strengths. Orders are priced in US dollars and packed according to the strength and pill count you select from our available options. Once an order is placed, we prepare and dispatch it promptly, and we treat any delivery estimate we provide as just that: an estimate, not a guarantee, since transit time can vary by destination within the United States. If a package needs a ZIP code adjustment or a delivery question comes up after dispatch, our support channels stay open to sort it out rather than leaving you to track it down alone.

Making Your Decision

Choosing Lopressor over another beta blocker usually comes down to a few concrete questions: does your prescriber want the dosing flexibility of an immediate-release tartrate tablet, or the steadier once-daily curve of an extended-release alternative; do you have kidney or liver considerations that favor one clearance pathway over another; and does our strength and pack-size lineup match the regimen you have been prescribed. If those answers point to metoprolol tartrate, we offer the strengths and package sizes to fill that prescription, backed by pharmacist support whenever a question comes up before or after you order.

Medically reviewed by
Lynette Ellis
Pharmacist
Updated November 7, 2026

Product specifications

Active ingredientMetoprolol
Drug classBeta blocker
Dosage formTablet
Available strengths12.5 mg, 25 mg, 50 mg, 100 mg
Route of administrationOral
StorageStore at 68°F to 77°F in a tightly closed, light-resistant container, and protect from moisture.
ATC codeC07AB02

Regulatory information

Approval statusMetoprolol is authorized for human medical use in the United States.
Prescription classificationMetoprolol tablets are available by prescription only from a licensed healthcare provider.

More information