Lopressor (Metoprolol) Tablets
Dosages
Lopressor 12.5 mg
| Quantity | Price per tablet | You save | Total price | |
|---|---|---|---|---|
| 60 | $0.91 | - | $54.80 | |
| 120 | $0.77 | $17.00 | $92.60 | |
| 240 | $0.73 | $43.20 | $176.00 | |
| 360 | $0.68 | $84.20 | $244.60 |
Lopressor 25 mg
| Quantity | Price per tablet | You save | Total price | |
|---|---|---|---|---|
| 60 | $0.67 | - | $40.20 | |
| 90 | $0.52 | $13.10 | $47.20 | |
| 120 | $0.46 | $25.30 | $55.10 | |
| 180 | $0.38 | $51.80 | $68.80 |
Lopressor 50 mg
| Quantity | Price per tablet | You save | Total price | |
|---|---|---|---|---|
| 90 | $0.52 | - | $46.70 | |
| 120 | $0.45 | $7.87 | $54.40 | |
| 180 | $0.41 | $20.50 | $72.90 | |
| 270 | $0.37 | $40.60 | $99.50 | |
| 360 | $0.35 | $61.40 | $125.40 |
Lopressor 100 mg
| Quantity | Price per tablet | You save | Total price | |
|---|---|---|---|---|
| 60 | $0.90 | - | $53.90 | |
| 90 | $0.75 | $13.05 | $67.80 | |
| 120 | $0.69 | $25.10 | $82.70 | |
| 180 | $0.61 | $51.70 | $110.00 | |
| 270 | $0.57 | $87.95 | $154.60 | |
| 360 | $0.55 | $125.50 | $197.90 |
Manufacturers
Payment & Shipping
Your order is carefully packed and ships within 24 hours. Here's the typical package.
Sized like a regular personal letter (9.4x4.3x0.3 inches), with no indication of its contents.
| Shipping Method | Estimated delivery |
|---|---|
| Express Free for orders over $300.00 | Estimated delivery to the U.S.: 4-7 days |
| Standard Free for orders over $200.00 | Estimated delivery to the U.S.: 14-21 days |










Discount Coupons
- Independence Day - July 4, 2026 10% JULY410
- Labor Day - September 7, 2026 7% LABOR07
- Thanksgiving - November 26, 2026 9% THANKS09
Brand Names
| Country | Brand Names |
|---|---|
United States | Toprol-XL |
United Kingdom | Betaloc Lopresor |
Canada | Apo-Metoprolol Lopresor |
Australia | Betaloc |
New Zealand | Betaloc Lopresor Slow-Lopresor |
FAQ
Description
If you are comparing beta blockers, the detail that matters most about Lopressor is its release profile: these are immediate-release metoprolol tartrate tablets, not the extended-release metoprolol succinate found in products like Toprol XL. That distinction changes how often the medicine is taken, how a missed dose behaves, and how closely blood pressure and heart rate need to be tracked between doses. We offer Lopressor in 12.5 mg, 25 mg, 50 mg, and 100 mg tablets across several package sizes, which lets a returning customer line up a refill with an existing prescription rather than guess at an unfamiliar strength.
Lopressor at a Glance: The Distinction That Matters
Because Lopressor is immediate-release, metoprolol tartrate reaches the bloodstream relatively quickly and clears faster than the succinate form. Depending on the indication, dose, and individual response, a prescriber may direct it to be taken once daily or in divided doses rather than treat it as interchangeable with a once-daily extended-release product. For someone switching from another beta blocker, or comparing a divided-dose tablet against a once-daily extended-release option, that dosing rhythm is often the deciding factor. We keep our strengths and package quantities aligned with that immediate-release identity so the product you add to your cart matches what a prescriber actually wrote for.
What Lopressor Is and Why We Carry It
Metoprolol belongs to the beta blocker class, and more specifically it is a beta-1 selective (cardioselective) agent, meaning it acts preferentially on the beta-1 receptors concentrated in heart tissue rather than the beta-2 receptors found in the lungs and blood vessels. Oral metoprolol tartrate is established for:
- Hypertension, used alone or alongside other blood pressure medicines
- Angina pectoris, to reduce the frequency and severity of chest pain episodes
- Early treatment following a heart attack, to help stabilize cardiac workload
We carry Lopressor because these are core, well-documented cardiovascular uses, and the tablet form gives customers a familiar, flexible way to fill a prescription that calls for metoprolol tartrate specifically rather than a combination product or the succinate salt.
Who Typically Considers Lopressor
Adults being treated for high blood pressure, angina, or recovering from a cardiac event are the usual candidates, generally under the direction of a physician who has reviewed their heart rate, blood pressure pattern, and other health conditions. A few practical factors tend to shape the decision between Lopressor and an alternative: how consistently someone can follow the prescribed dosing schedule, whether they have asthma or diabetes that calls for closer monitoring, whether they are pregnant, and whether dizziness from treatment initiation could affect driving or operating machinery. Customers managing hypertension as part of a broader regimen may also want to browse our blood pressure options to see how Lopressor fits alongside other medicines they may already be taking.
How Metoprolol Works in the Body
Metoprolol blocks beta-1 adrenergic receptors in the heart, which reduces the influence of adrenaline-driven signals that would otherwise speed up the heart rate and increase the force of each contraction. The practical result is a heart that beats more slowly and with less force, lowering the oxygen demand of heart muscle and easing the pressure exerted on artery walls. It also dampens renin release from the kidneys, which contributes further to blood pressure control over time.

Seeing that sequence laid out helps explain why metoprolol is not a fast-acting painkiller for chest discomfort, but rather a medicine that recalibrates how hard the heart has to work, hour after hour, as long as it is taken consistently.
Building a Daily Routine With Lopressor
Because Lopressor is immediate-release, it works best on a steady schedule. It may be prescribed once daily or in divided doses depending on the indication, total daily dose, and individual response. Taking it at the same times each day and consistently with or immediately after meals helps maintain a predictable effect and may reduce variation in absorption. Tablets are swallowed with a glass of water; they should not be split or crushed unless a prescriber or pharmacist confirms that the specific tablet can be handled that way. Dose strength and frequency are adjusted gradually by a prescriber based on heart rate and blood pressure response, which is why we offer four strengths rather than a single fixed dose. One routine point deserves particular attention: metoprolol should never be stopped abruptly. Sudden discontinuation can trigger rebound increases in heart rate and blood pressure, and in people with underlying coronary disease it has been associated with worsening chest pain or even a heart attack. Any change in dose or a decision to stop should be tapered under medical guidance.
Strengths and Package Sizes We Offer
We stock Lopressor tablets in the following strengths, each available in multiple pill counts so a customer can match the pack size to the expected treatment supply:
- 12.5 mg tablets in packs of 60, 120, 240, or 360 pills
- 25 mg tablets in packs of 60, 90, 120, or 180 pills
- 50 mg tablets in packs of 90, 120, 180, 270, or 360 pills
- 100 mg tablets in packs of 60, 90, 120, 180, 270, or 360 pills
Because some regimens use divided daily doses, larger pack sizes are often practical for ongoing hypertension or angina management, while a smaller pack can suit someone early in treatment whose dose may still be adjusted.
What to Expect and When
Some reduction in heart rate and blood pressure can appear within hours of the first doses, but the fuller blood pressure effect generally builds over one to two weeks of consistent use as the body adjusts. For angina, many people notice fewer or milder episodes during the first weeks of treatment, though the medicine works best as a steady preventive measure rather than something taken only when chest discomfort starts. After a heart attack, the treatment duration is determined by the prescriber based on the clinical situation and ongoing response; it should not be stopped or assigned an endpoint independently. Periodic check-ins to review heart rate, blood pressure, and overall response are a normal part of treatment.
Safety Priorities Before You Start
Metoprolol is not appropriate for everyone, and a few safety points deserve attention before starting or continuing treatment:
- It is contraindicated in severe bradycardia, higher-degree heart block or sick sinus syndrome without a functioning pacemaker, cardiogenic shock, and decompensated heart failure.
- People with severe peripheral circulation problems require particular caution because beta blockers can aggravate symptoms of reduced arterial circulation.
- People with asthma or COPD should use it cautiously, since even beta-1 selective agents can provoke airway narrowing at higher doses.
- People with diabetes should be aware that metoprolol can blunt the usual warning signs of low blood sugar, particularly a racing heartbeat, so blood sugar monitoring becomes more important.
- Pregnant patients should only use metoprolol when a prescriber judges the benefit to outweigh the risk, since beta-blocker exposure later in pregnancy has been linked to slowed fetal heart rate and low blood sugar in newborns.
- Dizziness, fatigue, or lightheadedness can occur, especially when treatment starts or a dose increases, which may affect driving or operating machinery until the response is known.
None of these points replace a prescriber's individualized assessment, but they outline the categories of risk that make metoprolol a prescription medicine rather than a casual over-the-counter choice.
Interactions and Practical Precautions
Metoprolol can interact with several other medicines and everyday substances. Combining it with calcium channel blockers such as verapamil or diltiazem can excessively slow the heart or worsen heart block, and stacking it with other beta blockers is generally avoided since the effects simply add up without added benefit. Other blood pressure medicines, including thiazide diuretics such as Hydrochlorothiazide, are commonly prescribed alongside metoprolol for hypertension, but the combined blood-pressure-lowering effect means dosing needs to be coordinated by a prescriber rather than adjusted independently. Clonidine requires particular caution: stopping clonidine while still taking a beta blocker like metoprolol can cause a dangerous rebound rise in blood pressure, so any clonidine taper is managed carefully around metoprolol use. NSAIDs can blunt metoprolol's blood-pressure-lowering effect over time, while certain antidepressants and antiarrhythmics that inhibit the CYP2D6 liver enzyme, such as fluoxetine, paroxetine, or quinidine, can raise metoprolol levels in the blood. Alcohol can intensify dizziness and should be used cautiously, especially early in treatment.
Comparing Lopressor With Other Beta Blockers
Lopressor is one of several beta blockers used for similar cardiovascular goals, and the right choice often comes down to dosing frequency, receptor selectivity, and how the body clears the drug. The comparisons below focus on distinctions that matter when deciding between Lopressor and a therapeutic alternative.
How Does Lopressor Compare to Tenormin?
Tenormin (atenolol) is another beta-1 selective beta blocker, but it is cleared mainly by the kidneys rather than the liver, which matters for people with reduced kidney function. Lopressor's hepatic metabolism, by contrast, makes liver function more relevant to its dosing.
How Does Lopressor Compare to Tenormin?
| Feature | Lopressor | Tenormin |
|---|---|---|
| Active ingredient | Metoprolol tartrate | Atenolol |
| Medication class | Cardioselective beta blocker | Cardioselective beta blocker |
| Common uses | Hypertension, angina, heart attack management | Hypertension, angina, heart attack recovery |
| Dosage form | Tablet | Tablet |
| Available strengths | 12.5 mg, 25 mg, 50 mg, 100 mg | 25 mg, 50 mg, 100 mg |
| Metabolic clearance | Primarily metabolized by the liver | Primarily eliminated unchanged by the kidneys |
How Does Lopressor Compare to Toprol-XL?
Toprol-XL is the extended-release metoprolol succinate formulation, built for once-daily dosing and a smoother blood-level curve, while Lopressor's immediate-release tartrate form may require divided daily doses and is prescribed according to the indication and individual response.
How Does Lopressor Compare to Toprol-XL?
| Feature | Lopressor | Toprol-XL |
|---|---|---|
| Active ingredient (salt) | Metoprolol tartrate | Metoprolol succinate |
| Release profile | Immediate release | Extended release |
| Dosage form | Tablet | Tablet |
| Primary uses | Hypertension, angina, heart attack recovery | Hypertension, angina, heart failure |
| Available strengths | 12.5 mg, 25 mg, 50 mg, 100 mg | 25 mg, 50 mg, 100 mg, 200 mg |
| Typical schedule | Often taken in multiple daily doses with meals | Designed for once-daily dosing |
How Does Lopressor Compare to Zebeta?
Zebeta (bisoprolol) is also beta-1 selective and, like Lopressor, is taken as a standard tablet, but it has a longer half-life that typically supports once-daily use, an option worth weighing against Lopressor regimens that require more frequent dosing.
How Does Lopressor Compare to Zebeta?
| Feature | Lopressor | Zebeta |
|---|---|---|
| Active ingredient | Metoprolol tartrate | Bisoprolol fumarate |
| Medication class | Cardioselective beta blocker | Cardioselective beta blocker |
| Common uses | Hypertension, angina, heart attack management | Management of hypertension |
| Dosage form | Tablet | Tablet |
| Available strengths | 12.5 mg, 25 mg, 50 mg, 100 mg | 5 mg, 10 mg |
| Action profile | Shorter duration of action | Longer duration of action |
None of these alternatives are identical substitutes; switching between them involves a dosing conversion that a prescriber manages, since milligram-for-milligram equivalence does not carry across different beta blockers.
Prescription Status and Access in the United States
Metoprolol is authorized for human medicinal use in the United States, and Lopressor tablets are classified as a prescription medicine here, meaning treatment is ordinarily directed by a licensed prescriber. Our ordering policy does not require you to submit a prescription document before we accept your order, and we do not ask you to upload one at checkout. This is a detail about how we accept orders, not a change to metoprolol's underlying prescription classification, and we think it is worth keeping those two facts distinct when you are deciding where to order from.
Ordering, Delivery, and Receiving Your Lopressor
We have operated PocketDrugGuide since 2018, and our team is reachable 24/7 by email or online chat, with a pharmacist available to answer questions about dosing, interactions, or anything else that comes up while you are deciding between strengths. Orders are priced in US dollars and packed according to the strength and pill count you select from our available options. Once an order is placed, we prepare and dispatch it promptly, and we treat any delivery estimate we provide as just that: an estimate, not a guarantee, since transit time can vary by destination within the United States. If a package needs a ZIP code adjustment or a delivery question comes up after dispatch, our support channels stay open to sort it out rather than leaving you to track it down alone.
Making Your Decision
Choosing Lopressor over another beta blocker usually comes down to a few concrete questions: does your prescriber want the dosing flexibility of an immediate-release tartrate tablet, or the steadier once-daily curve of an extended-release alternative; do you have kidney or liver considerations that favor one clearance pathway over another; and does our strength and pack-size lineup match the regimen you have been prescribed. If those answers point to metoprolol tartrate, we offer the strengths and package sizes to fill that prescription, backed by pharmacist support whenever a question comes up before or after you order.
Product specifications
| Active ingredient | Metoprolol |
|---|---|
| Drug class | Beta blocker |
| Dosage form | Tablet |
| Available strengths | 12.5 mg, 25 mg, 50 mg, 100 mg |
| Route of administration | Oral |
| Storage | Store at 68°F to 77°F in a tightly closed, light-resistant container, and protect from moisture. |
| ATC code | C07AB02 |
Regulatory information
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