Synthroid (Levothyroxine) Tablets

Synthroid
Generic:
Levothyroxine
Indications:
thyroid deficiency
Analogs:
Levothyroxine Levoxyl Unithroid Tirosint Euthyrox Eltroxin Liothyronine Cytomel Armour Thyroid Np Thyroid Thyrolar Nature Throid
Synthroid delivers synthetic levothyroxine in seven tablet strengths, from 25 mcg to 200 mcg, giving Canadian shoppers a consistent brand-name option for daily hypothyroidism treatment alongside the generic and brand alternatives we also cover in this guide.
In stock: 12 packs
AdultsPregnancyAllergiesDiabetesBreastfeedingChildrenDriving

Dosages

Synthroid 25 µg

Quantity Price per tablet You save Total price
240 C$0.25 - C$60.20
360 C$0.19 C$23.10 C$67.20

Synthroid 50 µg

Quantity Price per tablet You save Total price
240 C$0.28 - C$67.20
360 C$0.21 C$25.20 C$75.60

Synthroid 75 µg

Quantity Price per tablet You save Total price
240 C$0.29 - C$68.60
360 C$0.26 C$9.10 C$93.80

Synthroid 100 µg

Quantity Price per tablet You save Total price
100 C$0.50 - C$50.40
200 C$0.41 C$19.60 C$81.20
300 C$0.38 C$37.80 C$113.40

Synthroid 125 µg

Quantity Price per tablet You save Total price
120 C$0.48 - C$57.40
240 C$0.39 C$22.40 C$92.40
360 C$0.35 C$44.80 C$127.40

Synthroid 150 µg

Quantity Price per tablet You save Total price
100 C$0.64 - C$64.40
200 C$0.50 C$29.40 C$99.40
300 C$0.46 C$54.60 C$138.60

Synthroid 200 µg

Quantity Price per tablet You save Total price
100 C$0.78 - C$78.40
200 C$0.69 C$18.20 C$138.60
300 C$0.65 C$39.20 C$196.00

Manufacturers

Abbott LaboratoriesAbbVieAbbVie Inc.Aspen PharmacareGlaxoSmithKline plcJerome Stevens Pharmaceuticals Inc.Macleods Pharmaceuticals LimitedMerck Healthcare KGaAMerck KGaAMerck Santé SASPfizerSanofi-Aventis Deutschland GmbHUni-Pharma

Payment & Shipping

Package Example

Your order is carefully packed and ships within 24 hours. Here's the typical package.

Sized like a regular personal letter (24x11x0.7 cm), with no indication of its contents.

Front View
Front View
Side View
Side View
Back View
Back View
Shipping Times
Shipping MethodEstimated delivery
Express Free for orders over C$420.00Estimated delivery to Canada: 4-7 days
Standard Free for orders over C$280.00Estimated delivery to Canada: 14-21 days
EMSCanada Post
Payment Methods
VisaMastercardAmerican ExpressBitcoin, USDTInteracApple PayGoogle PayPayPal

Discount Coupons

  • Victoria Day - May 18, 2026 8% VICTORIA8
  • Canada Day - July 1, 2026 10% CANADADAY10
  • Labour Day - September 7, 2026 6% LABOUR6
  • Thanksgiving (Canada) - October 12, 2026 9% THANKS9
  • Boxing Day - December 26, 2026 12% BOXING12

Brand Names

Also known as (by country):
CountryBrand Names
Canada
Eltroxin
United States
Levoxyl Unithroid
United Kingdom
Eltroxin
France
Levothyrox Thyrofix
Australia
Eutroxsig Oroxine
New Zealand
Eltroxin
Germany
Euthyrox L-Thyroxin Henning
Italy
Eutirox
Belgium
Elthyrone Euthyrox Thyrax

FAQ

Take levothyroxine tablets by mouth with water on an empty stomach, usually 30 to 60 minutes before the first meal of the day. Calcium, iron, magnesium, aluminum-containing antacids, and some supplements can reduce absorption, so they are generally taken at least 4 hours apart. The daily strength and any dose changes must be individualized using thyroid blood tests and clinical response.

Calcium, iron, magnesium, aluminum-containing antacids, sucralfate, bile-acid sequestrants, sevelamer, and orlistat can reduce levothyroxine absorption. Other medicines, including warfarin and diabetes medicines, may require closer monitoring when levothyroxine is started or changed. Provide the prescriber and pharmacist with a current list of all medicines and supplements.

Description

Synthroid is the brand-name levothyroxine tablet we stock in seven strengths, from 25 mcg up to 200 mcg, and that strength range is the first practical fact for anyone comparing thyroid replacement options before ordering online in Canada. Levothyroxine is a synthetic form of the T4 thyroid hormone, and because hypothyroidism treatment depends on taking a stable dose consistently day after day, continuity of product and routine matters alongside the microgram strength printed on the label. Canadian shoppers weighing Synthroid against generic levothyroxine, Eltroxin, or Tirosint are deciding how each formulation fits their clinical needs, provincial coverage, local pharmacy availability, and the package size they actually need. This guide walks through that decision, then explains how we handle ordering, payment, and delivery for Synthroid across Canada.

Synthroid vs. Eltroxin, Generic Levothyroxine, and Tirosint: Comparing Your Options

Before choosing a package, it helps to compare Synthroid against other levothyroxine-based products Canadian patients and prescribers may discuss. The relevant differences usually come down to dosage form, non-medicinal ingredients, available strengths, and whether a patient can remain on the same product consistently.

Synthroid vs. Eltroxin

Eltroxin is another long-established brand-name levothyroxine tablet. Both Eltroxin and Synthroid supply the same active hormone, but fillers and colourant systems may differ between products and strengths. Prescribers commonly recommend confirming thyroid-stimulating hormone (TSH) levels after a switch between levothyroxine products rather than assuming that no monitoring is needed.

Key Differences: Synthroid vs. Eltroxin

FeatureSynthroidEltroxin
Active ingredientLevothyroxine sodiumLevothyroxine sodium
Therapeutic classThyroid hormoneThyroid hormone
Dosage formTabletTablet
Available strengths25 mcg, 50 mcg, 75 mcg, 100 mcg, 125 mcg, 150 mcg, 200 mcg50 mcg, 100 mcg
Formulation detailsStrength-specific colourants and lactose monohydrateDistinct brand excipient formulation; check individual tablet colourings

In practice, Eltroxin may suit someone already stabilized on that formulation, while Synthroid may suit someone who wants to continue an established Synthroid routine or needs one of the strengths we currently offer.

Synthroid vs. Generic Levothyroxine

Generic levothyroxine tablets contain the same active ingredient as Synthroid and may cost less per pill. Approved generic and brand products must meet applicable quality standards, but thyroid replacement is adjusted in small dose increments and can be sensitive to changes in absorption. Many patients and prescribers therefore prefer continuity with one product, whether generic or brand, and arrange TSH reassessment after a switch when appropriate.

Key Differences: Synthroid vs. Generic Levothyroxine

FeatureSynthroidLevothyroxine
Active ingredientLevothyroxine sodiumLevothyroxine sodium
Therapeutic classSynthetic thyroid hormone (T4)Synthetic thyroid hormone (T4)
Dosage formTabletTablet
Available strengths25 mcg, 50 mcg, 75 mcg, 100 mcg, 125 mcg, 150 mcg, 200 mcgVaries by generic manufacturer (multiple standard strengths)
Product typeOriginal brand-name formulationBioequivalent generic alternative; non-medicinal excipients may vary by maker

Generic levothyroxine may suit budget-focused buyers who can obtain the same manufacturer's product consistently, while Synthroid may suit those who specifically want to remain on the branded formulation. Brand status alone does not make one option clinically superior for every patient.

Synthroid vs. Tirosint

Tirosint is a notably different dosage form: a soft gelatin capsule containing a liquid levothyroxine formulation rather than a compressed tablet. It has a short excipient list and does not use the dyes or lactose found in some tablets, which can make it an alternative to discuss when sensitivity to tablet ingredients or absorption variability is a concern.

Key Differences: Synthroid vs. Tirosint

FeatureSynthroidTirosint
Active ingredientLevothyroxine sodiumLevothyroxine sodium
Dosage formTabletLiquid-filled capsule
Available strengths25 mcg, 50 mcg, 75 mcg, 100 mcg, 125 mcg, 150 mcg, 200 mcgMultiple micro-dosed capsule strengths (e.g., 13 mcg to 200 mcg)
Excipient profileContains conventional tablet binders, colour additives, and lactoseFormulated without dyes, lactose, or common tablet fillers

Tirosint can be worth discussing with a prescriber if lactose or dye sensitivity is a known issue, while Synthroid remains a practical tablet option for patients who tolerate its strength-specific ingredients and want to maintain an established routine.

What Makes Synthroid Different

Synthroid tablets are colour-coded by strength, but the non-medicinal ingredients differ by strength and may include lactose monohydrate and, in some strengths, azo or FD&C colourants such as tartrazine. Anyone with a known lactose or dye sensitivity should check the ingredient list for the exact strength before use. We offer 25 mcg, 50 mcg, 75 mcg, 100 mcg, 125 mcg, 150 mcg, and 200 mcg tablets, giving prescribers several options for individualized replacement dosing. Some patients choose Synthroid because remaining with the same branded formulation simplifies continuity between refills, although dose selection and follow-up testing remain more important than brand recognition alone. The manufacturer or distributor identified on the supplied pack should be checked when receiving an order, particularly if maintaining the same product is clinically important.

How Levothyroxine Works and What to Expect

Levothyroxine is a synthetic version of thyroxine (T4), the hormone an underactive thyroid gland fails to produce in sufficient quantity. Once absorbed, the body converts a portion of it to the more active T3 hormone, restoring metabolic signalling involved in energy use, heart rate, digestion, and temperature regulation. Because levothyroxine has a long half-life of roughly a week, Synthroid is usually taken once daily, and it takes about four to six weeks to approach a stable blood level after starting or changing a dose. Symptom improvement is typically gradual rather than immediate, and prescribers commonly wait about six to eight weeks before rechecking TSH after a dose adjustment. For most people, hypothyroidism treatment with Synthroid is a long-term, often lifelong, daily routine.

Synthroid Strengths, Package Sizes, and Value

We carry Synthroid in 25 mcg, 50 mcg, 75 mcg, 100 mcg, 125 mcg, 150 mcg, and 200 mcg tablets. The 25 mcg, 50 mcg, and 75 mcg strengths are available in packages of 240 or 360 pills; 100 mcg, 150 mcg, and 200 mcg are available in packages of 100, 200, or 300 pills; and 125 mcg is available in packages of 120, 240, or 360 pills. Because levothyroxine therapy is usually ongoing, a larger package at the same stable strength may provide better long-term value when its price per pill is lower and the quantity fits the patient's refill plan.

Synthroid 50 mcg Package Value Comparison

All prices on our Synthroid listings are shown in Canadian dollars, and checkout accepts Visa, Mastercard, American Express, and select cryptocurrency payments, so you can buy Synthroid online in the package size that matches your prescribed dose and refill schedule without guessing at a converted price.

Ordering Synthroid in Canada: Access and Regulatory Context

Levothyroxine is classified as a prescription medicine in Canada, and patients should use it with appropriate prescriber oversight. Health Canada's Drug Product Database lists authorized drug products by brand, strength, authorization holder, and Drug Identification Number (DIN), so checking the DIN, levothyroxine strength, manufacturer or distributor, and expiry information on the specific pack received is a sensible habit. Coverage is not uniform nationally: Canada does not operate one public drug formulary, and whether a particular product or strength is covered depends on the province or territory, the applicable public or private plan, and the specific DIN. Pharmacies and online pharmacy operations in Canada are regulated through provincial or territorial authorities rather than one national pharmacy licensing system. Our ordering policy is a separate matter: we do not require customers to upload a prescription document for us to accept a Synthroid order. That checkout policy does not change levothyroxine's prescription classification in Canada or replace medical supervision of thyroid treatment.

How to Take Synthroid

Levothyroxine absorption is sensitive to timing and to what else is in the stomach, so a consistent routine matters with Synthroid.

  • Take Synthroid at the same time every day, most commonly first thing in the morning on an empty stomach, with water.
  • Wait 30 to 60 minutes before eating breakfast; coffee can also reduce absorption, so keep its timing consistent and follow the interval recommended by your prescriber or pharmacist.
  • Do not switch between Synthroid, another brand, or a generic levothyroxine tablet without informing your prescriber, since thyroid function may need to be reassessed after a product change.
  • Split or crush a tablet only when a prescriber or pharmacist confirms that doing so is appropriate for the specific strength and patient.
  • If a dose is missed, follow the product instructions or advice from a prescriber or pharmacist. A dose may often be taken when remembered unless it is close to the next dose, but two doses should not be taken together unless specifically instructed.

Interactions and Precautions to Plan Around

Several common products interfere with how well levothyroxine is absorbed, and several medical conditions call for closer monitoring once Synthroid is started or adjusted.

  • Calcium supplements, iron supplements, and antacids containing aluminum or magnesium can reduce levothyroxine absorption; these are commonly separated from Synthroid by at least four hours.
  • Cholestyramine and similar bile acid sequestrants can substantially reduce absorption and require carefully separated dosing. High-fibre meals and soy products may also affect absorption when intake or timing changes.
  • Warfarin and other anticoagulants may need closer monitoring because restoring normal thyroid status can increase anticoagulant response.
  • Starting or adjusting Synthroid can change blood glucose control, so insulin or other diabetes treatment may need review alongside thyroid monitoring.

Effects associated with excessive thyroid hormone include palpitations, tremor, insomnia, heat intolerance, sweating, diarrhea, and unintended weight loss. Too little replacement may leave fatigue, cold intolerance, constipation, and low mood unresolved. Periodic TSH testing, interpreted with symptoms and other thyroid results when needed, should guide dose changes rather than symptoms alone. Chest pain, a rapid or irregular heartbeat, severe shortness of breath, or signs of a serious allergic reaction require prompt medical attention.

Who Should Use Extra Caution or Seek Medical Advice

Most adults use levothyroxine without difficulty, but several situations call for closer medical involvement before or during Synthroid use.

  • Pregnancy: treatment should continue because untreated hypothyroidism carries significant risk, but levothyroxine requirements commonly rise during pregnancy and TSH needs closer monitoring with dose adjustment as required.
  • Children: levothyroxine is an established treatment for pediatric hypothyroidism, including congenital hypothyroidism, but dosing is age- and weight-dependent and requires monitoring of thyroid function, growth, and development.
  • Known allergies or excipient sensitivities: check the lactose and colourant content of the specific Synthroid strength before use.
  • Diabetes: closer blood glucose monitoring may be needed after starting treatment or changing the dose.
  • Heart disease: older adults and people with coronary artery disease or rhythm disorders often need a lower starting dose and gradual adjustment under medical supervision.
  • Untreated adrenal insufficiency: thyroid hormone can precipitate an adrenal crisis, so adrenal insufficiency must be treated before levothyroxine is started.

Levothyroxine is compatible with breastfeeding at replacement doses and has no known direct effect on the ability to drive or operate machinery when used appropriately. If thyroid health is a broader concern, readers can explore our Thyroid section and discuss relevant treatment options with a prescriber.

Where to Buy Synthroid Online in Canada

We have supplied medicines to Canadian customers since 2018, and our checkout addresses the practical question of where to buy Synthroid in Canada without an unnecessary document-upload step. You can order Synthroid online by selecting the required strength and package size, paying by Visa, Mastercard, American Express, or cryptocurrency, and reaching our support team by email or online chat. A pharmacist is available 24/7 if you have questions about your strength or administration routine. Because levothyroxine dosing is individualized, keep your prescriber informed of the exact product and strength you use whenever you buy Synthroid online with us, even though our ordering process does not require a prescription upload.

Shipping and Delivery Across Canada

Canada's population is spread across a very large land area, and delivery timing to a dense urban corridor naturally differs from delivery to a smaller, northern, or remote community. We therefore treat every shipping estimate as an estimate rather than a guarantee. Express shipping costs C$41.99 and typically arrives in 4 to 7 business days with tracking, while standard shipping costs C$20.99 and typically takes 14 to 21 days without tracking. Both methods offer free shipping once an order passes the applicable threshold shown in Canadian dollars at checkout.

Estimated Delivery Times Across Canada

Destination CityExpressStandard
St. Catharines≈ 4 days≈ 21 days
Edmonton≈ 6 days≈ 17 days
Halifax≈ 4 days≈ 21 days
Sherbrooke≈ 7 days≈ 16 days
Kitchener≈ 7 days≈ 21 days
These estimates help compare delivery timing across select Canadian cities based on our experience with previous deliveries and are not guaranteed delivery dates.

Because Synthroid tablets should be stored at 20°C to 25°C, with excursions permitted between 15°C and 30°C, retrieve parcels promptly during winter cold spells or summer heat, particularly if the delivery point is an outdoor mailbox or community mail compartment. Once the order arrives, protect the tablets from light and moisture and check the pack before use. Keep the current product name, strength, and pharmacy or prescriber contact details available in case a drug plan or health professional needs to confirm the medicine at a future refill.

Medically reviewed by
Reynard Sparks
Pharmacologist
Updated August 18, 2026

Product specifications

Active ingredientLevothyroxine
Drug classThyroid hormone
Dosage formTablet
Available strengths25 mcg, 50 mcg, 75 mcg, 100 mcg, 125 mcg, 150 mcg, 200 mcg
RouteOral
StorageStore at 20°C to 25°C, with excursions permitted to 15°C to 30°C. Protect from light and moisture.
ATC codeH03AA01

Regulatory information

Canada: Euthyrox medicine status
Registration statusEuthyrox levothyroxine sodium tablets are listed as authorized prescription drug products in Health Canada's Drug Product Database; verify the DIN and strength for the specific pack supplied.
Prescription statusLevothyroxine is a prescription medicine in Canada and requires a prescription from an authorized prescriber.
Canadian authorization holderMerck Canada Inc. is the Canadian authorization holder for Euthyrox products listed in the Drug Product Database.
Public coverageThere is no single Canada-wide public drug formulary; coverage for levothyroxine depends on the province or territory, the public plan, and the specific DIN.
Safety monitoringSuspected adverse reactions may be reported to Health Canada through the Canada Vigilance Program.

More information