| Quantity | Price per tablet | You save | Total price | |
|---|---|---|---|---|
| 20 | $5.75 | - | $115.00 | |
| 30 | $5.57 | $5.50 | $167.00 | |
| 60 | $5.12 | $38.00 | $307.00 | |
| 90 | $4.60 | $103.50 | $414.00 | |
| 120 | $4.27 | $178.00 | $512.00 | |
| 180 | $3.92 | $329.00 | $706.00 | |
| 270 | $3.59 | $584.50 | $968.00 | |
| 360 | $3.41 | $842.00 | $1,228.00 |
| Quantity | Price per tablet | You save | Total price | |
|---|---|---|---|---|
| 10 | $9.10 | - | $91.00 | |
| 20 | $7.15 | $39.00 | $143.00 | |
| 30 | $6.47 | $79.00 | $194.00 | |
| 60 | $5.97 | $188.00 | $358.00 | |
| 90 | $5.69 | $307.00 | $512.00 | |
| 120 | $5.49 | $433.00 | $659.00 | |
| 180 | $5.09 | $722.00 | $916.00 | |
| 270 | $4.70 | $1,188.00 | $1,269.00 | |
| 360 | $4.31 | $1,724.00 | $1,552.00 |
| Quantity | Price per tablet | You save | Total price | |
|---|---|---|---|---|
| 10 | $36.50 | - | $365.00 | |
| 20 | $30.50 | $120.00 | $610.00 |
Your order is carefully packed and ships within 24 hours. Here's the typical package.
Sized like a regular personal letter (9.4x4.3x0.3 inches), with no indication of its contents.
| Shipping Method | Estimated delivery |
|---|---|
| Express Free for orders over $300.00 | Estimated delivery to the U.S.: 4-7 days |
| Standard Free for orders over $200.00 | Estimated delivery to the U.S.: 14-21 days |
| Country | Brand Names |
|---|---|
| United States | Astagraf XL |
| United Kingdom | Adoport Advagraf |
| Canada | Advagraf |
| Australia | Advagraf |
Several drugs are particularly well-known in the pharmaceutical industry for their exceptional ability to treat various medical ailments. Prograf is among such medications. Prograf is frequently administered to patients undergoing transplantation and to those suffering from particular autoimmune illnesses. It is essential in suppressing the immune system to avoid organ rejection or lessen autoimmune disease symptoms.
Prograf, sometimes referred to as tacrolimus in its generic form, is an immunosuppressive drug. It limits the body's immunological response by blocking the functioning of specific immune system cells. This immunosuppressive effect is essential in keeping the recipient's immune system from rejecting transplanted organs such as the liver, heart, kidneys, or lungs.
Prograf's capacity to connect to a protein known as FK-binding protein-12 (FKBP-12) is part of its mode of action. Then, this Prograf-FKBP-12 combination inhibits the calcineurin enzyme. The immune response is mediated by T-lymphocytes, a subset of white blood cells activated by calcineurin. Prograf reduces the activation of T-lymphocytes and their subsequent proliferation by blocking calcineurin, which in turn attenuates the immunological response.
Uses of Prograf| Indication | Initial Oral Dose | Maintenance Oral Dose Range | Monitoring |
|---|---|---|---|
| Kidney Transplantation | 0.10 - 0.20 mg/kg/day in 2 divided doses | 0.05 - 0.15 mg/kg/day in 2 divided doses, adjusted based on clinical response and tacrolimus trough levels | Tacrolimus trough levels (e.g., 5-15 ng/mL) should be monitored regularly, typically 2-3 times per week initially, then less frequently |
| Liver Transplantation | 0.10 - 0.20 mg/kg/day in 2 divided doses | 0.05 - 0.15 mg/kg/day in 2 divided doses, adjusted based on clinical response and tacrolimus trough levels | Tacrolimus trough levels (e.g., 5-20 ng/mL) should be monitored regularly, typically 2-3 times per week initially, then less frequently |
| Heart Transplantation | 0.075 - 0.15 mg/kg/day in 2 divided doses | 0.05 - 0.10 mg/kg/day in 2 divided doses, adjusted based on clinical response and tacrolimus trough levels | Tacrolimus trough levels (e.g., 5-15 ng/mL) should be monitored regularly, typically 2-3 times per week initially, then less frequently |
| Lung Transplantation | 0.075 - 0.15 mg/kg/day in 2 divided doses | 0.05 - 0.10 mg/kg/day in 2 divided doses, adjusted based on clinical response and tacrolimus trough levels | Tacrolimus trough levels (e.g., 5-15 ng/mL) should be monitored regularly, typically 2-3 times per week initially, then less frequently |
Prograf has drawbacks even though it works wonders in controlling autoimmune disorders and preventing organ rejection. Among the most common adverse effects of using Prograf are:
Prograf, or tacrolimus, is a potent immunosuppressive drug frequently used to treat autoimmune diseases and facilitate organ donation. Healthcare practitioners can maximize the use of this medication while lowering patient risks by being aware of its mechanism of action, indications, and possible side effects. In spite of its adverse effects, Prograf is still a vital weapon in the fight against autoimmune illnesses and organ rejection, providing countless people all over the world with hope for better results and a higher standard of living.
I just received my tacrolimus order. What should I look for to make sure the ingredient and strength are correct?
Check the package label for "tacrolimus," the strength ordered - 0.5 mg, 1 mg, or 5 mg - and that it is an oral capsule. Also compare the dosage form, manufacturer name, lot number, expiration date, and any capsule imprint if present. Do not use the capsules until any mismatch is clarified.
Before I order, can you tell me how much shelf life the tacrolimus capsules will have left?
The exact expiration date depends on the package supplied and is printed on its label. We cannot promise a specific remaining shelf life before an order is received; check the labeled expiration date before use.
My husband takes tacrolimus after a kidney transplant. Can he still have grapefruit juice with breakfast?
No. Grapefruit and grapefruit juice can raise tacrolimus blood levels and increase the risk of toxicity, including kidney and neurologic effects. He should avoid grapefruit products and keep the transplant team informed about dietary or medication changes.
| Active ingredient | Tacrolimus |
|---|---|
| Drug class | Calcineurin inhibitor immunosuppressant |
| Dosage form | Capsule |
| Available strengths | 0.5 mg, 1 mg, 5 mg |
| Route | Oral |
| Storage | Store the capsules between 41°F and 77°F in the original container, protected from moisture. |
| ATC code | L04AD02 |
This product has 28 ratings, but only 4 written reviews so far. Share your experience and help other customers.
They sent my Prograf order quickly.
Several package sizes were available, and the 1 mg, 120-unit tacrolimus order fit what I needed.
I found it a good value.
The order arrived in good shape.
