Sustiva (Efavirenz)

Sustiva
4.739 ratingsReviews
Generic:
Efavirenz
Indications:
HIV
Analogs:
Efavirenz Stocrin Atripla Symfi Nevirapine Rilpivirine Etravirine Doravirine Dolutegravir Biktarvy Dovato Triumeq Delstrigo Edurant Intelence Pifeltro Viramune
AdultsPregnancyAllergiesDiabetesBreastfeedingChildrenDriving

Dosages

Sustiva 200 mg

Quantity Price per tablet You save Total price
10 £6.67 - £66.67
20 £6.22 £8.89 £124.45
30 £5.95 £21.48 £178.53
60 £5.25 £85.19 £314.84
90 £4.86 £162.98 £437.07
120 £4.57 £251.13 £548.93
180 £4.29 £428.18 £771.91
270 £4.15 £678.57 £1,121.57
360 £4.01 £954.89 £1,445.30

Sustiva 600 mg

Quantity Price per tablet You save Total price
10 £8.00 - £80.01
20 £7.78 £4.44 £155.57
30 £7.31 £20.74 £219.28
60 £6.63 £82.23 £397.81
90 £6.26 £157.05 £563.01
120 £5.90 £251.87 £708.20
180 £5.54 £443.00 £997.12
270 £5.18 £761.54 £1,398.63
360 £4.82 £1,144.54 £1,735.69

Manufacturers

Alkem Laboratories Ltd.Bristol-Myers SquibbCipla LimitedMerck Sharp & DohmeMylanTeva Pharmaceutical Industries

Payment & Delivery

Package Example

Your order is carefully packed and ships within 24 hours. Here's the typical package.

Sized like a regular personal letter (24x11x0.7 cm), with no indication of its contents.

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Front View
Side View
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Back View
Back View
Delivery Times
Delivery MethodEstimated delivery
Express Free for orders over £222.24Estimated delivery to the UK: 4-7 days
Standard Free for orders over £148.16Estimated delivery to the UK: 14-21 days
EMSRoyal Mail
Payment Methods
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Discount Coupons

  • New Year's Day - 1 January 2026 9% NEWYEAR9
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  • St Patrick's Day - 17 March 2026 5% PATRICK5
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  • May Day - 1 May 2026 5% MAYDAY5
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  • Christmas Day - 25 December 2026 10% XMAS10
  • Boxing Day - 26 December 2026 10% BOXING10
  • New Year's Eve - 31 December 2026 8% NYE8

Brand Names

Also known as (by country):
CountryBrand Names
United Kingdom
Efavirenz Mylan Efavirenz Teva
Australia
Stocrin
Canada
Teva-Efavirenz

FAQ

Efavirenz is a prescription-only medicine when obtained from local UK pharmacies. Our store policy allows you to order it without a prescription and have it sent by mail. Efavirenz should be used as part of combination HIV treatment.

Take unused or expired efavirenz to a pharmacy or another authorised medicines take-back service where available. Do not share it with anyone else, and do not dispose of it in household waste or down the toilet unless a pharmacist specifically advises this.

A generic efavirenz product contains efavirenz, the active ingredient associated with Sustiva. The manufacturer, tablet or capsule appearance, inactive ingredients and packaging may differ between products.

Efavirenz use during pregnancy needs assessment by an HIV and maternity specialist. It may be appropriate to start or continue in some circumstances, but treatment should not be changed independently. Breastfeeding is generally avoided while taking efavirenz because the medicine passes into breast milk and HIV can be transmitted to an infant.

Efavirenz capsules and tablets are taken by mouth as part of a combination antiretroviral regimen, not on their own. A common adult regimen is 600 mg once daily, usually at bedtime and on an empty stomach, but the exact dose and accompanying HIV medicines must be selected for the individual.

Description

Brand Name: Sustiva
Active Ingredient: efavirenz
Indication: For use in combination treatment of HIV infection (AIDS)
Company Name: DuPont Pharmaceuticals
Availability: FDA granted accelerated approval in September 1998; FDA granted traditional (full) approval based on long-term efficacy in February 2000

Sustiva - Drug for HIV TreatmentGeneral Information

Though patients with AIDS manage their HIV infection with a variety of medications (sometimes in combination), no medication has been fully approved by the FDA based on long-term outcomes until recently. Sustiva (efavirenz), produced by DuPont Pharmaceuticals, was the first anti-HIV medication fully approved by the FDA in February 2000. This was due to long-term data demonstrating the drug's efficacy in combating HIV infection.

In September 1998, the FDA first granted Sustiva expedited approval so that people with AIDS could use it. Only when combined with other anti-HIV treatments that the patient has never had before the drug may be used to treat AIDS. If Sustiva is taken alone, the AIDS virus may become resistant to the medication. Adults and children over three who are HIV-positive can use Sustiva; three capsules should be taken once a day.

Sustiva: Results of a Clinical Study 

Sustiva has been demonstrated to lower blood levels of HIV (the so-called viral load) and raises CD4 cells, a subset of immune system cells when used with other anti-HIV medications. According to two clinical studies, patients receiving Sustiva in addition to two other "antiretroviral" medications (such as lamivudine, nelfinavir, or zidovudine) saw a longer duration of treatment and a higher reduction in their viral load than those receiving the medication in any other combination. This response to treatment was shown in one trial to last up to 110 weeks, and the investigation is ongoing. 

According to Dr. Cal Cohen, Director of the Community Research Initiative of New England, HIV medications must not only bring the virus level in the blood down to below detectable levels but also maintain it this way for as long as possible. The FDA's long-term Sustiva data clearly demonstrate that this medication can successfully achieve this goal when used with other medications.

What You Should Know

Patients taking Sustiva most frequently report mild to moderate rash, dizziness, sleeplessness, drowsiness, and poor concentration as side effects. Early in the course of treatment, these symptoms usually go away in two to four weeks. Children get severe rashes more frequently and with a greater incidence than adults. Patients should refrain from using heavy machinery or driving if they are experiencing sleepiness or other nervous system symptoms. Pregnant women should not use Sustiva since animal studies have linked it to congenital disabilities.

Medically reviewed by
Jennifer Bowles
Pharmacologist
Updated 11 August 2026

Customer questions

Asked by Hannah, London, United Kingdom

I'm Hannah in London and need to plan my next supply. Will the efavirenz have enough time left before its expiry date when it arrives?

Answered by Support team

We cannot guarantee a minimum remaining shelf life before an order is packed. Check the expiry date printed on the received package before use and keep the medicine in its tightly closed container at 25°C.

Asked by Louise, Bristol, United Kingdom

I'm Louise and use the combined contraceptive pill. Can I rely on it while taking efavirenz?

Answered by Support team
Medical reviewed by Lynette Ellis

Efavirenz can reduce the effectiveness of some hormonal contraceptives. Use a reliable barrier method as well and ask your HIV clinician or pharmacist to review the most suitable contraception for your treatment regimen.

Product specifications

Active ingredientEfavirenz
Drug classNon-nucleoside reverse transcriptase inhibitor (NNRTI)
Dosage formCapsules and tablets
Available strengths200 mg, 600 mg
RouteOral
StorageStore at 25°C; excursions permitted between 15°C and 30°C. Keep the container tightly closed.
ATC codeJ05AG03

Regulatory information

United Kingdom: medicine status
Prescription statusEfavirenz is a prescription-only medicine in the United Kingdom and should be prescribed as part of combination antiretroviral treatment for HIV.
Product registrationThe product name Sustiva and the listed 200 mg and 600 mg strengths do not by themselves confirm a current UK marketing authorisation for a particular pack; the authorisation must be checked for the exact product, strength and dosage form.
NHS medicine informationThe NHS provides patient medicine information for efavirenz, including how it is used and important precautions.Safety monitoringSuspected side effects should be reported through the MHRA Yellow Card Scheme by patients, carers or healthcare professionals.

More information