Sustiva (Efavirenz)

Sustiva
4.69 ratingsReviews
Generic:
Efavirenz
Indications:
HIV
Analogs:
Efavirenz Stocrin Atripla Symfi Nevirapine Rilpivirine Etravirine Doravirine Dolutegravir Biktarvy Dovato Triumeq Delstrigo Edurant Intelence Pifeltro Viramune
AdultsPregnancyAllergiesDiabetesBreastfeedingChildrenDriving

Dosages

Sustiva 200 mg

Quantity Price per tablet You save Total price
10 $9.00 - $90.00
20 $8.40 $12.00 $168.00
30 $8.03 $29.00 $241.00
60 $7.08 $115.00 $425.00
90 $6.56 $220.00 $590.00
120 $6.18 $339.00 $741.00
180 $5.79 $578.00 $1,042.00
270 $5.61 $916.00 $1,514.00
360 $5.42 $1,289.00 $1,951.00

Sustiva 600 mg

Quantity Price per tablet You save Total price
10 $10.80 - $108.00
20 $10.50 $6.00 $210.00
30 $9.87 $28.00 $296.00
60 $8.95 $111.00 $537.00
90 $8.44 $212.00 $760.00
120 $7.97 $340.00 $956.00
180 $7.48 $598.00 $1,346.00
270 $6.99 $1,028.00 $1,888.00
360 $6.51 $1,545.00 $2,343.00

Manufacturers

Alkem Laboratories Ltd.Bristol-Myers SquibbCipla LimitedMerck Sharp & DohmeMylanTeva Pharmaceutical Industries

Payment & Shipping

Package Example

Your order is carefully packed and ships within 24 hours. Here's the typical package.

Sized like a regular personal letter (9.4x4.3x0.3 inches), with no indication of its contents.

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Shipping Times
Shipping MethodEstimated delivery
Express Free for orders over $300.00Estimated delivery to the U.S.: 4-7 days
Standard Free for orders over $200.00Estimated delivery to the U.S.: 14-21 days
EMSUSPS
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Discount Coupons

  • Independence Day - July 4, 2026 10% JULY410
  • Labor Day - September 7, 2026 7% LABOR07
  • Thanksgiving - November 26, 2026 9% THANKS09

Brand Names

Also known as (by country):
CountryBrand Names
United Kingdom
Efavirenz Mylan Efavirenz Teva
Canada
Teva-Efavirenz
Australia
Stocrin

FAQ

Efavirenz is a prescription-only medicine when purchased from local US pharmacies. However, our store policy allows you to place an order without providing a prescription, and the medicine can be sent by mail.

Whether a particular efavirenz tablet can be split, crushed, or chewed cannot be determined from the available product data. Do not alter tablets unless the instructions for the received package or a pharmacist specifically confirm that it is appropriate. Efavirenz capsules may have different administration instructions from tablets.

The exact manufacturer for an individual order is not confirmed in advance. Check the received package label for the manufacturer, along with the active ingredient, strength, dosage form, lot number, and expiration date.

Pregnancy requires prompt assessment by an HIV clinician because efavirenz has potential fetal-risk concerns, particularly with early pregnancy exposure, and the benefits and alternatives must be considered for the individual treatment regimen. Do not stop antiretroviral treatment on your own. Breastfeeding should be avoided in the United States for people with HIV; efavirenz passes into human milk, and breastfeeding can transmit HIV to an infant.

Efavirenz is taken by mouth as part of combination antiretroviral therapy; it must not be used alone to treat HIV. The usual adult regimen is 600 mg once daily, commonly at bedtime and on an empty stomach because food can increase efavirenz levels and side effects. The prescribed dose may differ for children or when other medicines affect efavirenz.

Description

Brand Name: Sustiva
Active Ingredient: efavirenz
Indication: For use in combination treatment of HIV infection (AIDS)
Company Name: DuPont Pharmaceuticals
Availability: FDA granted accelerated approval in September 1998; FDA granted traditional (full) approval based on long-term efficacy in February 2000

Sustiva - Drug for HIV TreatmentGeneral Information

Though patients with AIDS manage their HIV infection with a variety of medications (sometimes in combination), no medication has been fully approved by the FDA based on long-term outcomes until recently. Sustiva (efavirenz), produced by DuPont Pharmaceuticals, was the first anti-HIV medication fully approved by the FDA in February 2000. This was due to long-term data demonstrating the drug's efficacy in combating HIV infection.

In September 1998, the FDA first granted Sustiva expedited approval so that people with AIDS could use it. Only when combined with other anti-HIV treatments that the patient has never had before the drug may be used to treat AIDS. If Sustiva is taken alone, the AIDS virus may become resistant to the medication. Adults and children over three who are HIV-positive can use Sustiva; three capsules should be taken once a day.

Sustiva: Results of a Clinical Study 

Sustiva has been demonstrated to lower blood levels of HIV (the so-called viral load) and raises CD4 cells, a subset of immune system cells when used with other anti-HIV medications. According to two clinical studies, patients receiving Sustiva in addition to two other "antiretroviral" medications (such as lamivudine, nelfinavir, or zidovudine) saw a longer duration of treatment and a higher reduction in their viral load than those receiving the medication in any other combination. This response to treatment was shown in one trial to last up to 110 weeks, and the investigation is ongoing. 

According to Dr. Cal Cohen, Director of the Community Research Initiative of New England, HIV medications must not only bring the virus level in the blood down to below detectable levels but also maintain it this way for as long as possible. The FDA's long-term Sustiva data clearly demonstrate that this medication can successfully achieve this goal when used with other medications.

What You Should Know

Patients taking Sustiva most frequently report mild to moderate rash, dizziness, sleeplessness, drowsiness, and poor concentration as side effects. Early in the course of treatment, these symptoms usually go away in two to four weeks. Children get severe rashes more frequently and with a greater incidence than adults. Patients should refrain from using heavy machinery or driving if they are experiencing sleepiness or other nervous system symptoms. Pregnant women should not use Sustiva since animal studies have linked it to congenital disabilities.

Medically reviewed by
Jennifer Bowles
Pharmacologist
Updated August 11, 2026

Customer questions

Asked by Amanda Reed, Dallas, United States

I used efavirenz capsules before and want to make sure I order the right form. Does your store sell capsules or tablets?

Answered by Support team

Our catalog lists efavirenz in capsules and tablets. Available strengths are 200 mg and 600 mg; confirm the dosage form and strength that match your prescription before ordering.

Asked by Marcus Hill, Houston, United States

I drive early in the morning for work. Can efavirenz affect driving?

Answered by Support team
Medical reviewed by Jennifer Bowles

Yes. Efavirenz can cause dizziness, drowsiness, impaired concentration, or unusual dreams, especially when treatment is started. Avoid driving or operating machinery until you know how it affects you.

Product specifications

Active ingredientEfavirenz
Drug classNon-nucleoside reverse transcriptase inhibitor (NNRTI)
Dosage formCapsules and tablets
Available strengths200 mg, 600 mg
RouteOral
StorageStore at 77°F; excursions permitted between 59°F and 86°F. Keep the container tightly closed.
ATC codeJ05AG03

Regulatory information

United States: Sustiva medicine status
FDA registration statusSustiva (efavirenz) was FDA-approved under NDA 020972 for capsules and NDA 021360 for 600 mg tablets.
Prescription statusSustiva is a prescription-only antiretroviral medicine in the United States.
Safety monitoringSerious suspected adverse events should be reported to the FDA MedWatch program; efavirenz labeling includes important neuropsychiatric, nervous-system, hepatic, rash, and pregnancy-related safety warnings.

More information